FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070231010> ?p ?o ?g. }

• W2070231010 endingPage "10" @default.
• W2070231010 startingPage "1" @default.
• W2070231010 abstract "Interleukin-33 appears to play important roles in the induction of allergic airway inflammation. However, whether IL-33 is involved in airway remodeling remains unclear. Because fibrocytes contribute to tissue remodeling in the setting of chronic inflammation, we examined the effects of IL-33 on fibrocyte functions. Fibrocytes were generated in vitro from peripheral blood mononuclear cells by culturing in the presence of platelet derived growth factors and the cells were stimulated with IL-33. IL-33 enhanced cell proliferation,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>α</mml:mi></mml:mrow></mml:math>-SMA expression, and pro-MMP-9 activity by the fibrocytes without increasing endogenous transforming growth factor-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>1 production. Fibrocytes constitutively expressed IL-13 and IL-5, and their production was augmented by stimulation with IL-33. Dexamethasone inhibited the functions of fibrocytes, but IL-33 made fibrocytes slightly refractory to the inhibitory effect of dexamethasone in terms of IL-13 production. Montelukast suppressed IL-13 production by nonstimulated fibrocytes but not those stimulated by IL-33. These findings suggest that IL-33 is involved in the airway remodeling process through its modulation of fibrocyte function independent of antigen stimulation. IL-33 might partially reduce the therapeutic effects of glucocorticoid and cysteinyl leukotriene receptor antagonist on fibrocyte-mediated Th2 responses." @default.
• W2070231010 created "2016-06-24" @default.
• W2070231010 creator A5025754055 @default.
• W2070231010 creator A5026882721 @default.
• W2070231010 creator A5065996447 @default.
• W2070231010 creator A5066275650 @default.
• W2070231010 creator A5087488592 @default.
• W2070231010 creator A5087805967 @default.
• W2070231010 date "2014-01-01" @default.
• W2070231010 modified "2023-10-14" @default.
• W2070231010 title "IL-33 Enhanced the Proliferation and Constitutive Production of IL-13 and IL-5 by Fibrocytes" @default.
• W2070231010 cites W1575966267 @default.
• W2070231010 cites W1625157530 @default.
• W2070231010 cites W1743498587 @default.
• W2070231010 cites W1759915280 @default.
• W2070231010 cites W1967763945 @default.
• W2070231010 cites W1969818245 @default.
• W2070231010 cites W1971523219 @default.
• W2070231010 cites W1973621813 @default.
• W2070231010 cites W1979732414 @default.
• W2070231010 cites W1980642591 @default.
• W2070231010 cites W1981654793 @default.
• W2070231010 cites W1989106684 @default.
• W2070231010 cites W2010452771 @default.
• W2070231010 cites W2016970487 @default.
• W2070231010 cites W2017014747 @default.
• W2070231010 cites W2020887684 @default.
• W2070231010 cites W2029525660 @default.
• W2070231010 cites W2032532760 @default.
• W2070231010 cites W2041407803 @default.
• W2070231010 cites W2060715078 @default.
• W2070231010 cites W2080725704 @default.
• W2070231010 cites W2085581142 @default.
• W2070231010 cites W2087691206 @default.
• W2070231010 cites W2090500320 @default.
• W2070231010 cites W2113654390 @default.
• W2070231010 cites W2127751349 @default.
• W2070231010 cites W2130847047 @default.
• W2070231010 cites W2136348136 @default.
• W2070231010 cites W2140083164 @default.
• W2070231010 cites W2147848520 @default.
• W2070231010 cites W2160712143 @default.
• W2070231010 cites W2167768045 @default.
• W2070231010 cites W4248565951 @default.
• W2070231010 cites W4252082388 @default.
• W2070231010 cites W4294352168 @default.
• W2070231010 doi "https://doi.org/10.1155/2014/738625" @default.
• W2070231010 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4005215" @default.
• W2070231010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24822215" @default.
• W2070231010 hasPublicationYear "2014" @default.
• W2070231010 type Work @default.
• W2070231010 sameAs 2070231010 @default.
• W2070231010 citedByCount "15" @default.
• W2070231010 countsByYear W20702310102015 @default.
• W2070231010 countsByYear W20702310102016 @default.
• W2070231010 countsByYear W20702310102017 @default.
• W2070231010 countsByYear W20702310102020 @default.
• W2070231010 countsByYear W20702310102021 @default.
• W2070231010 countsByYear W20702310102022 @default.
• W2070231010 countsByYear W20702310102023 @default.
• W2070231010 crossrefType "journal-article" @default.
• W2070231010 hasAuthorship W2070231010A5025754055 @default.
• W2070231010 hasAuthorship W2070231010A5026882721 @default.
• W2070231010 hasAuthorship W2070231010A5065996447 @default.
• W2070231010 hasAuthorship W2070231010A5066275650 @default.
• W2070231010 hasAuthorship W2070231010A5087488592 @default.
• W2070231010 hasAuthorship W2070231010A5087805967 @default.
• W2070231010 hasBestOaLocation W20702310101 @default.
• W2070231010 hasConcept C134018914 @default.
• W2070231010 hasConcept C137061746 @default.
• W2070231010 hasConcept C142724271 @default.
• W2070231010 hasConcept C185592680 @default.
• W2070231010 hasConcept C202751555 @default.
• W2070231010 hasConcept C203014093 @default.
• W2070231010 hasConcept C24998067 @default.
• W2070231010 hasConcept C2776914184 @default.
• W2070231010 hasConcept C2778690821 @default.
• W2070231010 hasConcept C55493867 @default.
• W2070231010 hasConcept C68324877 @default.
• W2070231010 hasConcept C71924100 @default.
• W2070231010 hasConcept C74172505 @default.
• W2070231010 hasConcept C75786153 @default.
• W2070231010 hasConcept C86803240 @default.
• W2070231010 hasConceptScore W2070231010C134018914 @default.
• W2070231010 hasConceptScore W2070231010C137061746 @default.
• W2070231010 hasConceptScore W2070231010C142724271 @default.
• W2070231010 hasConceptScore W2070231010C185592680 @default.
• W2070231010 hasConceptScore W2070231010C202751555 @default.
• W2070231010 hasConceptScore W2070231010C203014093 @default.
• W2070231010 hasConceptScore W2070231010C24998067 @default.
• W2070231010 hasConceptScore W2070231010C2776914184 @default.
• W2070231010 hasConceptScore W2070231010C2778690821 @default.
• W2070231010 hasConceptScore W2070231010C55493867 @default.
• W2070231010 hasConceptScore W2070231010C68324877 @default.
• W2070231010 hasConceptScore W2070231010C71924100 @default.
• W2070231010 hasConceptScore W2070231010C74172505 @default.
• W2070231010 hasConceptScore W2070231010C75786153 @default.
• W2070231010 hasConceptScore W2070231010C86803240 @default.

• next