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- W2070243397 abstract "The preparation and muscarinic activities of a number of 5-alkyl substituted analogues of the dioxolane of Fourneau are described. Muscarinic activity decreases rapidly when the alkyl chain lengthens, moreover a change from parasympathomimetic into parasympatholytic activity occurs. The stereochemical aspects with regard to the 5-position are considered. The synthesis and cholinolytic effect of 2-methyl-c-5-propyl-r-4-trimethylammoniomethyl-1,3-dioxolane iodide and the corresponding 4,5-trans compound are described. Copyright © 1972 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim" @default.
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- W2070243397 date "2010-09-02" @default.
- W2070243397 modified "2023-09-25" @default.
- W2070243397 title "Relation between structure and cholinergic activity. I. Synthesis and muscarinic activity of 5-alkyl-2-methyl-4-trimethylammoniomethyl-1,3-dioxolane iodides" @default.
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- W2070243397 doi "https://doi.org/10.1002/recl.19720910813" @default.
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