Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070268956> ?p ?o ?g. }
- W2070268956 endingPage "1159" @default.
- W2070268956 startingPage "1151" @default.
- W2070268956 abstract "Electrospun nanofibers can be readily assembled into various types of scaffolds for applications in neural tissue engineering. The objective of this study is to examine and understand the unique patterns of neurite outgrowth from primary dorsal root ganglia (DRG) cultured on scaffolds of electrospun nanofibers having different orders, structures, and surface properties. We found that the neurites extended radially outward from the DRG main body without specific directionality when cultured on a nonwoven mat of randomly oriented nanofibers. In contrast, the neurites preferentially extended along the long axis of fiber when cultured on a parallel array of aligned nanofibers. When seeded at the border between regions of aligned and random nanofibers, the same DRG simultaneously expressed aligned and random neurite fields in response to the underlying nanofibers. When cultured on a double-layered scaffold where the nanofibers in each layer were aligned along a different direction, the neurites were found to be dependent on the fiber density in both layers. This biaxial pattern clearly demonstrates that neurite outgrowth can be influenced by nanofibers in different layers of a scaffold, rather than the topmost layer only. Taken together, these results will provide valuable information pertaining to the design of nanofiber scaffolds for neuroregenerative applications, as well as the effects of topology on neurite outgrowth, growth cone guidance, and axonal regeneration." @default.
- W2070268956 created "2016-06-24" @default.
- W2070268956 creator A5000647986 @default.
- W2070268956 creator A5041556229 @default.
- W2070268956 creator A5047704870 @default.
- W2070268956 creator A5052418512 @default.
- W2070268956 creator A5052626674 @default.
- W2070268956 date "2009-04-27" @default.
- W2070268956 modified "2023-10-18" @default.
- W2070268956 title "Neurite Outgrowth on Nanofiber Scaffolds with Different Orders, Structures, and Surface Properties" @default.
- W2070268956 cites W1569535372 @default.
- W2070268956 cites W1661921944 @default.
- W2070268956 cites W1967880112 @default.
- W2070268956 cites W1972113511 @default.
- W2070268956 cites W1976672709 @default.
- W2070268956 cites W1978184578 @default.
- W2070268956 cites W1984417662 @default.
- W2070268956 cites W1997651801 @default.
- W2070268956 cites W1998546382 @default.
- W2070268956 cites W2008769396 @default.
- W2070268956 cites W2011670388 @default.
- W2070268956 cites W2015277484 @default.
- W2070268956 cites W2017100977 @default.
- W2070268956 cites W2018811490 @default.
- W2070268956 cites W2019575274 @default.
- W2070268956 cites W2021703447 @default.
- W2070268956 cites W2032195777 @default.
- W2070268956 cites W2035317617 @default.
- W2070268956 cites W2038634187 @default.
- W2070268956 cites W2040096698 @default.
- W2070268956 cites W2042898787 @default.
- W2070268956 cites W2047608799 @default.
- W2070268956 cites W2064746368 @default.
- W2070268956 cites W2065420625 @default.
- W2070268956 cites W2074006600 @default.
- W2070268956 cites W2074305677 @default.
- W2070268956 cites W2075755310 @default.
- W2070268956 cites W2088686740 @default.
- W2070268956 cites W2093483666 @default.
- W2070268956 cites W2096222358 @default.
- W2070268956 cites W2099821568 @default.
- W2070268956 cites W2100169867 @default.
- W2070268956 cites W2138240749 @default.
- W2070268956 cites W2139908236 @default.
- W2070268956 cites W2140295532 @default.
- W2070268956 cites W2148304597 @default.
- W2070268956 cites W2152524298 @default.
- W2070268956 cites W2158563642 @default.
- W2070268956 doi "https://doi.org/10.1021/nn900070z" @default.
- W2070268956 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2765554" @default.
- W2070268956 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19397333" @default.
- W2070268956 hasPublicationYear "2009" @default.
- W2070268956 type Work @default.
- W2070268956 sameAs 2070268956 @default.
- W2070268956 citedByCount "231" @default.
- W2070268956 countsByYear W20702689562012 @default.
- W2070268956 countsByYear W20702689562013 @default.
- W2070268956 countsByYear W20702689562014 @default.
- W2070268956 countsByYear W20702689562015 @default.
- W2070268956 countsByYear W20702689562016 @default.
- W2070268956 countsByYear W20702689562017 @default.
- W2070268956 countsByYear W20702689562018 @default.
- W2070268956 countsByYear W20702689562019 @default.
- W2070268956 countsByYear W20702689562020 @default.
- W2070268956 countsByYear W20702689562021 @default.
- W2070268956 countsByYear W20702689562022 @default.
- W2070268956 countsByYear W20702689562023 @default.
- W2070268956 crossrefType "journal-article" @default.
- W2070268956 hasAuthorship W2070268956A5000647986 @default.
- W2070268956 hasAuthorship W2070268956A5041556229 @default.
- W2070268956 hasAuthorship W2070268956A5047704870 @default.
- W2070268956 hasAuthorship W2070268956A5052418512 @default.
- W2070268956 hasAuthorship W2070268956A5052626674 @default.
- W2070268956 hasBestOaLocation W20702689562 @default.
- W2070268956 hasConcept C105702510 @default.
- W2070268956 hasConcept C113246987 @default.
- W2070268956 hasConcept C135903288 @default.
- W2070268956 hasConcept C136229726 @default.
- W2070268956 hasConcept C171250308 @default.
- W2070268956 hasConcept C185592680 @default.
- W2070268956 hasConcept C187761678 @default.
- W2070268956 hasConcept C192562407 @default.
- W2070268956 hasConcept C202751555 @default.
- W2070268956 hasConcept C2779227376 @default.
- W2070268956 hasConcept C2779530196 @default.
- W2070268956 hasConcept C49892992 @default.
- W2070268956 hasConcept C55493867 @default.
- W2070268956 hasConcept C71924100 @default.
- W2070268956 hasConcept C86803240 @default.
- W2070268956 hasConcept C89429830 @default.
- W2070268956 hasConcept C91129048 @default.
- W2070268956 hasConceptScore W2070268956C105702510 @default.
- W2070268956 hasConceptScore W2070268956C113246987 @default.
- W2070268956 hasConceptScore W2070268956C135903288 @default.
- W2070268956 hasConceptScore W2070268956C136229726 @default.
- W2070268956 hasConceptScore W2070268956C171250308 @default.
- W2070268956 hasConceptScore W2070268956C185592680 @default.
- W2070268956 hasConceptScore W2070268956C187761678 @default.