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- W2070290069 abstract "Animal model and clinical studies indicate that type 1 diabetes (T1D) results from T cell-mediated autoimmune destruction of insulin-producing pancreatic beta-cells. This review discusses the knowledge gained from animal models about the nature of the autoreactive T cells that cause T1D and the possible basis for their development. Based on this information, the possible positive and negative aspects of various antigen-specific and non-specific immunotherapies, which could potentially prevent the onset of T1D in at risk individuals, are discussed." @default.
- W2070290069 created "2016-06-24" @default.
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- W2070290069 date "2005-11-01" @default.
- W2070290069 modified "2023-10-14" @default.
- W2070290069 title "Of mice and men: use of animal models to identify possible interventions for the prevention of autoimmune type 1 diabetes in humans" @default.
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- W2070290069 doi "https://doi.org/10.1016/j.it.2005.08.012" @default.
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