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• W2070290148 abstract "To study the bufadienolides in the Chinese traditional drug “Ch'an Su” and their cytotoxic activity. Various chromatographic techniques were used to isolate the constituents, and their structures were elucidated through physical and spectroscopic data. Twenty compounds were isolated, and eighteen were evaluated in vitro for their cytotoxic activity against A-549 and K-562 cells. Compound 1 (bufalin 3β-acrylic ester) was a new bufadienolide and exhibited the most potent activity against the two tumor cell lines with IC50 values of 7.16 and 6.83 nmol · L−1. The relationships between structure and activity are discussed." @default.
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• W2070290148 date "2014-08-01" @default.
• W2070290148 modified "2023-10-12" @default.
• W2070290148 title "A new bufadienolide with cytotoxic activity from the Chinese traditional drug Ch'an Su" @default.
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• W2070290148 doi "https://doi.org/10.1016/s1875-5364(14)60095-9" @default.
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