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• W2070299319 abstract "Different forms of neural cell adhesion molecule (N-CAM) are generated by alternative splicing of primary transcripts and considered to have distinct biological functions. We cloned cDNAs encoding a new form of N-CAMs from theXenopusheart cDNA library. Comparison of the sequences with chicken and mouse N-CAMs revealed that these clones code for ssd-form N-CAM. We demonstrate by Northern blot analysis that the ssd form is the major form expressed in theXenopusadult heart. We obtained two types of ssd-form N-CAM, which are transcripts from N-CAM 1 and N-CAM 2 genes. Both types contain muscle specific domain (MSD) but not π domain. Northern blot analysis also indicated that this form is not expressed in adult brain, in which ld-form N-CAM is the main N-CAM expressed. It is possible that high levels of specific expression of ssd-form N-CAM are related with the differentiation of cardiac muscles." @default.
• W2070299319 created "2016-06-24" @default.
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• W2070299319 date "1998-04-01" @default.
• W2070299319 modified "2023-10-16" @default.
• W2070299319 title "Molecular Cloning of ssd-Form Neural Cell Adhesion Molecules (N-CAMs) as the Major Form inXenopusHeart" @default.
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• W2070299319 doi "https://doi.org/10.1006/bbrc.1998.8347" @default.
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