FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070306479> ?p ?o ?g. }

• W2070306479 endingPage "8219" @default.
• W2070306479 startingPage "8213" @default.
• W2070306479 abstract "Chromogranin A is a low-affinity, high-capacity Ca2+ binding protein, postulated to be responsible for the Ca2+ buffering role of secretory vesicles, and has been found only in the soluble portions of the vesicular proteins. Contrary to the generally accepted notion of chromogranin A existing as a soluble matrix protein, chromogranin A bound to the secretory vesicle membrane at the intravesicular pH of 5.5 and freed from the membrane when the pH was raised to a more physiological pH of 7.5. Trypsin digestion studies of the vesicle membrane suggested that chromogranin A interacts with the protein component(s) on the intravesicular side of the membrane. Furthermore, in a study using 14 synthetic chromogranin A peptides which represent various portions of chromogranin A, a segment in the N-terminal region (residues 18-37) was shown to bind to the vesicle membrane in a pH-dependent manner. The pH-dependent vesicle membrane binding property of chromogranin A appears to be of fundamental physiological importance with regard to the potential roles of chromogranin A in secretory vesicle biogenesis, particularly in segregating secretory vesicle membranes from others in the trans-Golgi network, and also in transmitting extravesicular signals such as inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate for Ca2+ release or uptake to the inside of vesicles." @default.
• W2070306479 created "2016-06-24" @default.
• W2070306479 creator A5060698282 @default.
• W2070306479 date "1993-08-01" @default.
• W2070306479 modified "2023-10-16" @default.
• W2070306479 title "pH-Dependent association of chromogranin A with secretory vesicle membrane and a putative membrane binding region of chromogranin A" @default.
• W2070306479 cites W128815045 @default.
• W2070306479 cites W1481469889 @default.
• W2070306479 cites W1482605569 @default.
• W2070306479 cites W1500397819 @default.
• W2070306479 cites W1503394109 @default.
• W2070306479 cites W1511284320 @default.
• W2070306479 cites W1515292518 @default.
• W2070306479 cites W1527771705 @default.
• W2070306479 cites W1531532159 @default.
• W2070306479 cites W1531765690 @default.
• W2070306479 cites W1543140440 @default.
• W2070306479 cites W1552233144 @default.
• W2070306479 cites W1559446815 @default.
• W2070306479 cites W1569722645 @default.
• W2070306479 cites W1571930658 @default.
• W2070306479 cites W1641104439 @default.
• W2070306479 cites W1679079033 @default.
• W2070306479 cites W1780761338 @default.
• W2070306479 cites W1965846839 @default.
• W2070306479 cites W1970203013 @default.
• W2070306479 cites W1986718205 @default.
• W2070306479 cites W1994176565 @default.
• W2070306479 cites W2007709380 @default.
• W2070306479 cites W2018599257 @default.
• W2070306479 cites W2022286262 @default.
• W2070306479 cites W2034608686 @default.
• W2070306479 cites W2040494354 @default.
• W2070306479 cites W2053418558 @default.
• W2070306479 cites W2069260204 @default.
• W2070306479 cites W2088698582 @default.
• W2070306479 cites W2090006697 @default.
• W2070306479 cites W2092657822 @default.
• W2070306479 cites W2095234743 @default.
• W2070306479 cites W2095450147 @default.
• W2070306479 cites W2100837269 @default.
• W2070306479 cites W2119116080 @default.
• W2070306479 cites W2132276518 @default.
• W2070306479 cites W2151924284 @default.
• W2070306479 cites W2154787431 @default.
• W2070306479 cites W2159960669 @default.
• W2070306479 cites W2168526937 @default.
• W2070306479 cites W2226650408 @default.
• W2070306479 cites W2242835881 @default.
• W2070306479 cites W2262883706 @default.
• W2070306479 doi "https://doi.org/10.1021/bi00083a023" @default.
• W2070306479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8347621" @default.
• W2070306479 hasPublicationYear "1993" @default.
• W2070306479 type Work @default.
• W2070306479 sameAs 2070306479 @default.
• W2070306479 citedByCount "50" @default.
• W2070306479 countsByYear W20703064792012 @default.
• W2070306479 countsByYear W20703064792013 @default.
• W2070306479 countsByYear W20703064792017 @default.
• W2070306479 countsByYear W20703064792018 @default.
• W2070306479 crossrefType "journal-article" @default.
• W2070306479 hasAuthorship W2070306479A5060698282 @default.
• W2070306479 hasConcept C119062480 @default.
• W2070306479 hasConcept C130316041 @default.
• W2070306479 hasConcept C144647389 @default.
• W2070306479 hasConcept C156399914 @default.
• W2070306479 hasConcept C158617107 @default.
• W2070306479 hasConcept C185592680 @default.
• W2070306479 hasConcept C203014093 @default.
• W2070306479 hasConcept C204232928 @default.
• W2070306479 hasConcept C2909863526 @default.
• W2070306479 hasConcept C41625074 @default.
• W2070306479 hasConcept C49039625 @default.
• W2070306479 hasConcept C55493867 @default.
• W2070306479 hasConcept C77231918 @default.
• W2070306479 hasConcept C86803240 @default.
• W2070306479 hasConcept C95444343 @default.
• W2070306479 hasConceptScore W2070306479C119062480 @default.
• W2070306479 hasConceptScore W2070306479C130316041 @default.
• W2070306479 hasConceptScore W2070306479C144647389 @default.
• W2070306479 hasConceptScore W2070306479C156399914 @default.
• W2070306479 hasConceptScore W2070306479C158617107 @default.
• W2070306479 hasConceptScore W2070306479C185592680 @default.
• W2070306479 hasConceptScore W2070306479C203014093 @default.
• W2070306479 hasConceptScore W2070306479C204232928 @default.
• W2070306479 hasConceptScore W2070306479C2909863526 @default.
• W2070306479 hasConceptScore W2070306479C41625074 @default.
• W2070306479 hasConceptScore W2070306479C49039625 @default.
• W2070306479 hasConceptScore W2070306479C55493867 @default.
• W2070306479 hasConceptScore W2070306479C77231918 @default.
• W2070306479 hasConceptScore W2070306479C86803240 @default.
• W2070306479 hasConceptScore W2070306479C95444343 @default.
• W2070306479 hasIssue "32" @default.
• W2070306479 hasLocation W20703064791 @default.
• W2070306479 hasLocation W20703064792 @default.
• W2070306479 hasOpenAccess W2070306479 @default.
• W2070306479 hasPrimaryLocation W20703064791 @default.
• W2070306479 hasRelatedWork W1482138322 @default.

• next