Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070307440> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2070307440 endingPage "93" @default.
- W2070307440 startingPage "93" @default.
- W2070307440 abstract "Hypertonic saline has been recently recommended for treatment of patients in hemorrhagic shock. Infusion of hypertonic saline at different periods in cases of uncontrolled hemorrhagic shock was studied in rats. The animals were divided into six groups: in group 1 uncontrolled hemorrhagic shock was induced by tail resection and no hypertonic saline was administered; in group 2 hypertonic saline was administered 5 minutes after shock was induced; in group 3 hypertonic saline was administered 15 minutes after shock was induced; in group 4 hypertonic saline was administered 30 minutes after shock was induced; in group 5 hypertonic saline was administered 60 minutes after shock was induced; and in group 6 hypertonic saline was administered 120 minutes after shock was induced. Tail resection in rats in group 1 was followed by a mean +/- SEM bleeding of 2.7 +/- .03 mL in 5 minutes. Infusion of hypertonic saline after 5 and 15 minutes resulted in additional bleeding of 6.3 +/- 1.0 mL and 3.8 +/- 0.5 mL, respectively, and a drop in mean arterial pressure to 36 +/- 8 mm Hg and 56 +/- 9 mm Hg, respectively. Mortality was 80% in group 2 and 53% in group 3. Infusion of hypertonic saline 30 and 60 minutes after shock was induced did not alter bleeding, mean arterial pressure, or survival. Infusion of hypertonic saline within 15 minutes of hemorrhagic shock resulted in increased bleeding, hypotension, and early death. Infusion 30 minutes or later did not alter these variables. This potential danger of early hypertonic saline therapy should be considered in the treatment of patients in trauma." @default.
- W2070307440 created "2016-06-24" @default.
- W2070307440 creator A5006736327 @default.
- W2070307440 creator A5018021013 @default.
- W2070307440 creator A5027380317 @default.
- W2070307440 creator A5083450587 @default.
- W2070307440 date "1992-01-01" @default.
- W2070307440 modified "2023-10-02" @default.
- W2070307440 title "Hypertonic Saline Treatment of Uncontrolled Hemorrhagic Shock at Different Periods From Bleeding" @default.
- W2070307440 cites W1636221908 @default.
- W2070307440 cites W1970293762 @default.
- W2070307440 cites W1981701153 @default.
- W2070307440 cites W1985156473 @default.
- W2070307440 cites W199174002 @default.
- W2070307440 cites W2008158517 @default.
- W2070307440 cites W2010094703 @default.
- W2070307440 cites W2017271911 @default.
- W2070307440 cites W2029225964 @default.
- W2070307440 cites W2088117829 @default.
- W2070307440 cites W2370744434 @default.
- W2070307440 cites W2412463002 @default.
- W2070307440 cites W2417465322 @default.
- W2070307440 cites W2424078360 @default.
- W2070307440 cites W71720282 @default.
- W2070307440 doi "https://doi.org/10.1001/archsurg.1992.01420010107017" @default.
- W2070307440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1734856" @default.
- W2070307440 hasPublicationYear "1992" @default.
- W2070307440 type Work @default.
- W2070307440 sameAs 2070307440 @default.
- W2070307440 citedByCount "59" @default.
- W2070307440 countsByYear W20703074402012 @default.
- W2070307440 countsByYear W20703074402014 @default.
- W2070307440 countsByYear W20703074402017 @default.
- W2070307440 countsByYear W20703074402021 @default.
- W2070307440 crossrefType "journal-article" @default.
- W2070307440 hasAuthorship W2070307440A5006736327 @default.
- W2070307440 hasAuthorship W2070307440A5018021013 @default.
- W2070307440 hasAuthorship W2070307440A5027380317 @default.
- W2070307440 hasAuthorship W2070307440A5083450587 @default.
- W2070307440 hasConcept C117277713 @default.
- W2070307440 hasConcept C126322002 @default.
- W2070307440 hasConcept C141071460 @default.
- W2070307440 hasConcept C2776452961 @default.
- W2070307440 hasConcept C2777397205 @default.
- W2070307440 hasConcept C2777953023 @default.
- W2070307440 hasConcept C2778165595 @default.
- W2070307440 hasConcept C2781300812 @default.
- W2070307440 hasConcept C3017567848 @default.
- W2070307440 hasConcept C42219234 @default.
- W2070307440 hasConcept C71924100 @default.
- W2070307440 hasConcept C84393581 @default.
- W2070307440 hasConceptScore W2070307440C117277713 @default.
- W2070307440 hasConceptScore W2070307440C126322002 @default.
- W2070307440 hasConceptScore W2070307440C141071460 @default.
- W2070307440 hasConceptScore W2070307440C2776452961 @default.
- W2070307440 hasConceptScore W2070307440C2777397205 @default.
- W2070307440 hasConceptScore W2070307440C2777953023 @default.
- W2070307440 hasConceptScore W2070307440C2778165595 @default.
- W2070307440 hasConceptScore W2070307440C2781300812 @default.
- W2070307440 hasConceptScore W2070307440C3017567848 @default.
- W2070307440 hasConceptScore W2070307440C42219234 @default.
- W2070307440 hasConceptScore W2070307440C71924100 @default.
- W2070307440 hasConceptScore W2070307440C84393581 @default.
- W2070307440 hasIssue "1" @default.
- W2070307440 hasLocation W20703074401 @default.
- W2070307440 hasLocation W20703074402 @default.
- W2070307440 hasOpenAccess W2070307440 @default.
- W2070307440 hasPrimaryLocation W20703074401 @default.
- W2070307440 hasRelatedWork W2076390552 @default.
- W2070307440 hasRelatedWork W2164586945 @default.
- W2070307440 hasRelatedWork W2270133592 @default.
- W2070307440 hasRelatedWork W2356036990 @default.
- W2070307440 hasRelatedWork W2367021317 @default.
- W2070307440 hasRelatedWork W2389368918 @default.
- W2070307440 hasRelatedWork W2390617604 @default.
- W2070307440 hasRelatedWork W2748681096 @default.
- W2070307440 hasRelatedWork W2799628582 @default.
- W2070307440 hasRelatedWork W2245202200 @default.
- W2070307440 hasVolume "127" @default.
- W2070307440 isParatext "false" @default.
- W2070307440 isRetracted "false" @default.
- W2070307440 magId "2070307440" @default.
- W2070307440 workType "article" @default.