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- W2070365900 abstract "Groups of breast-feeding and non-breast (bottle) feeding mothers who were seronegative for rubella virus during pregnancy were immunized with subcutaneously administered live rubella virus vaccine during the immediate post-partum period. All infants of these women were subsequently immunized at 15 months of age with live measles, mumps and rubella vaccine. The rubella antibody activity in the mothers and the infants was determined by standard hemagglutination inhibition (HAI) test and enzymelinked immunoassay (ELISA, IgG) before and six months after immunization. All infants developed significant rubella specific HAI and ELISA antibody response. The mean antibody titers in bottle-fed infants (HAI 77, ELISA 7961) were higher than breastfed infants (HAI 69, ELISA 6400), although the difference was not statistically significant (P>0.05). These observations suggest that although shedding of infectious rubella vaccine virus in the breast milk has been associated with post-partum immunization of seronegative women, acquisition of the virus by the infants in the neonatal period does not appear to have significant adverse influence on the success of routine rubella immunization at 15 months of age. The importance of the subtle differences observed here remains to be defined." @default.
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- W2070365900 date "1984-04-01" @default.
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- W2070365900 title "POST-PARTUM MATERNAL RUBELLA IMMUNIZATION AND EFFECT OF BREAST FEEDING ON SUBSEQUENT IMMUNIZATION OF THE INFANTS" @default.
- W2070365900 doi "https://doi.org/10.1203/00006450-198404001-01173" @default.
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