Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070476783> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2070476783 abstract "High-resolution cytogenetics were applied to leucocytes, bone marrow, and tumors of 8 retinoblastoma (Rb) patients in search of microdeletions or subtle rearrangements and in order to determine clonal evolution. Four of 9 tumors (Rb1, Rb6.1, Rb6.2, and Rb8) showed a deletion in the characteristic region on 13q while 2 others (Rb3 and Rb4) were hemizygous for chromosome 13 in approximately one-third of the cells. Our study presents a particularly high incidence of chromosome 13 anomalies as compared to the previously published data. Furthermore, comparison of karyotypes of 3 significant cases (Rb1, Rb6, and Rb8) allows the reconstruction of the necessary steps in the evolution of retinoblastoma. It also shows the need for a double mutation in tumor development, both in hereditary and non-hereditary cases. High-resolution chromosome analysis of retinoblastoma patients provides a rare opportunity to study the succession of events necessary for tumor development." @default.
- W2070476783 created "2016-06-24" @default.
- W2070476783 creator A5023235839 @default.
- W2070476783 creator A5078337939 @default.
- W2070476783 date "1990-08-01" @default.
- W2070476783 modified "2023-10-03" @default.
- W2070476783 title "Chromosome evolution and high-resolution analysis of leucocytes, bone marrow, and tumor cells of retinoblastoma patients" @default.
- W2070476783 cites W147310725 @default.
- W2070476783 cites W1970232559 @default.
- W2070476783 cites W1971468932 @default.
- W2070476783 cites W1972299795 @default.
- W2070476783 cites W1980139594 @default.
- W2070476783 cites W1983545492 @default.
- W2070476783 cites W1983982755 @default.
- W2070476783 cites W1989976890 @default.
- W2070476783 cites W1992450235 @default.
- W2070476783 cites W2013138326 @default.
- W2070476783 cites W2023454517 @default.
- W2070476783 cites W2027610342 @default.
- W2070476783 cites W2028969319 @default.
- W2070476783 cites W2043955588 @default.
- W2070476783 cites W2059936703 @default.
- W2070476783 cites W2070634082 @default.
- W2070476783 cites W2071620217 @default.
- W2070476783 cites W2073278946 @default.
- W2070476783 cites W2075858335 @default.
- W2070476783 cites W2077858999 @default.
- W2070476783 cites W2085619712 @default.
- W2070476783 cites W2111486924 @default.
- W2070476783 cites W2129788616 @default.
- W2070476783 cites W2132719811 @default.
- W2070476783 cites W2150148423 @default.
- W2070476783 doi "https://doi.org/10.1002/ajmg.1320360417" @default.
- W2070476783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2389803" @default.
- W2070476783 hasPublicationYear "1990" @default.
- W2070476783 type Work @default.
- W2070476783 sameAs 2070476783 @default.
- W2070476783 citedByCount "4" @default.
- W2070476783 crossrefType "journal-article" @default.
- W2070476783 hasAuthorship W2070476783A5023235839 @default.
- W2070476783 hasAuthorship W2070476783A5078337939 @default.
- W2070476783 hasConcept C104317684 @default.
- W2070476783 hasConcept C127313418 @default.
- W2070476783 hasConcept C138626823 @default.
- W2070476783 hasConcept C142724271 @default.
- W2070476783 hasConcept C174475383 @default.
- W2070476783 hasConcept C203014093 @default.
- W2070476783 hasConcept C2776577112 @default.
- W2070476783 hasConcept C2780007613 @default.
- W2070476783 hasConcept C2992684800 @default.
- W2070476783 hasConcept C3020199158 @default.
- W2070476783 hasConcept C30481170 @default.
- W2070476783 hasConcept C502942594 @default.
- W2070476783 hasConcept C53226629 @default.
- W2070476783 hasConcept C54355233 @default.
- W2070476783 hasConcept C62649853 @default.
- W2070476783 hasConcept C71924100 @default.
- W2070476783 hasConcept C86803240 @default.
- W2070476783 hasConceptScore W2070476783C104317684 @default.
- W2070476783 hasConceptScore W2070476783C127313418 @default.
- W2070476783 hasConceptScore W2070476783C138626823 @default.
- W2070476783 hasConceptScore W2070476783C142724271 @default.
- W2070476783 hasConceptScore W2070476783C174475383 @default.
- W2070476783 hasConceptScore W2070476783C203014093 @default.
- W2070476783 hasConceptScore W2070476783C2776577112 @default.
- W2070476783 hasConceptScore W2070476783C2780007613 @default.
- W2070476783 hasConceptScore W2070476783C2992684800 @default.
- W2070476783 hasConceptScore W2070476783C3020199158 @default.
- W2070476783 hasConceptScore W2070476783C30481170 @default.
- W2070476783 hasConceptScore W2070476783C502942594 @default.
- W2070476783 hasConceptScore W2070476783C53226629 @default.
- W2070476783 hasConceptScore W2070476783C54355233 @default.
- W2070476783 hasConceptScore W2070476783C62649853 @default.
- W2070476783 hasConceptScore W2070476783C71924100 @default.
- W2070476783 hasConceptScore W2070476783C86803240 @default.
- W2070476783 hasLocation W20704767831 @default.
- W2070476783 hasLocation W20704767832 @default.
- W2070476783 hasOpenAccess W2070476783 @default.
- W2070476783 hasPrimaryLocation W20704767831 @default.
- W2070476783 hasRelatedWork W101514373 @default.
- W2070476783 hasRelatedWork W2070476783 @default.
- W2070476783 hasRelatedWork W2121906452 @default.
- W2070476783 hasRelatedWork W2349128217 @default.
- W2070476783 hasRelatedWork W2349538798 @default.
- W2070476783 hasRelatedWork W2365315221 @default.
- W2070476783 hasRelatedWork W2384385974 @default.
- W2070476783 hasRelatedWork W2418540521 @default.
- W2070476783 hasRelatedWork W2430217650 @default.
- W2070476783 hasRelatedWork W2430467182 @default.
- W2070476783 isParatext "false" @default.
- W2070476783 isRetracted "false" @default.
- W2070476783 magId "2070476783" @default.
- W2070476783 workType "article" @default.