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• W2070479314 abstract "T1ρ-weighted MRI is a novel basis for generating tissue contrast. However, it suffers from sensitivity to B1 inhomogeneity. First, excitation with a spatially varying B1 causes flip-angle artifacts and second, spin locking with an inhomogeneous B1 results in non-uniform T1ρ contrast. In this study, we overcome the former complication with a specially designed spin-locking pulse sequence and we successfully obtain T1ρ-weighted images with a surface coil. In this pulse sequence, the spin-lock pulse was divided into segments of equal duration and alternating phase. This “self-compensating” T1ρ-preparatory pulse sequence was analyzed and the effect of an inhomogeneous B1 field was simulated using the Bloch equations. T1ρ-weighted MR images of a phantom and a human knee joint in vivo were obtained on a clinical scanner with a surface coil to demonstrate the utility of the pulse sequence. The self-compensating T1ρ-prepared pulses sequence resulted in substantially reduced image artifacts compared to the conventional, single-phase spin-lock pulse." @default.
• W2070479314 created "2016-06-24" @default.
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• W2070479314 date "2004-04-01" @default.
• W2070479314 modified "2023-09-25" @default.
• W2070479314 title "T1ρ-weighted MRI using a surface coil to transmit spin-lock pulses" @default.
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• W2070479314 doi "https://doi.org/10.1016/j.jmr.2004.01.007" @default.
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