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• W2070498101 abstract "Combined pituitary hormone deficiency (CPHD) is characterized by impaired production of GH and one or more of the other anterior pituitary hormones. Prophet of Pit-1 (PROP-1), one of the pituitary specific homeodomain transcription factors, is involved in the differentiation of the anterior pituitary cells (somatotrophs, lactotrophs, thyrotrophs, and gonadotrophs), and PROP-1 gene mutations may interfere with the development of these cells, resulting in CPHD." @default.
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• W2070498101 date "2003-01-01" @default.
• W2070498101 modified "2023-10-17" @default.
• W2070498101 title "Familial Combined Pituitary Hormone Deficiency due to a Novel Mutation R99Q in the Hot Spot Region of Prophet of Pit-1 Presenting as Constitutional Growth Delay" @default.
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• W2070498101 doi "https://doi.org/10.1210/jc.2001-011872" @default.
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