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- W2070524739 abstract "Identification of the normal microglial population in human and rodent nervous tissue using lectin–histochemistry Mistletoe iectin–1 (ML–1) and Ricinus communis agglutinin–120 (RCA–1) both possess D–galactose–specific surface–binding sites. They were used to selectively identify microglial populations in aldehyde–fixed normal brain tissue by lectin immunohistochemistry on paraffin and frozen sections. Mistletoe lectin–1 was superior to RCA–1 in labelling microglia in the rat brain, whereas RCA–1 labelled human microglia better than ML–1. Thus, RCA–1 and ML–1 supplement each other for identifying microglial in human and rodent central nervous system tissues. The high reproducibility of the results and the applicability of the technique to routine histology, using formalin–fixed tissue, should facilitate study of the histogenesis and role of microglia in the CNS." @default.
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- W2070524739 date "1988-06-01" @default.
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- W2070524739 title "IDENTIFICATION OF THE NORMAL MICROGLIAL POPULATION IN HUMAN AND RODENT NERVOUS TISSUE USING LECTIN–HISTOCHEMISTRY" @default.
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- W2070524739 doi "https://doi.org/10.1111/j.1365-2990.1988.tb00883.x" @default.
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