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• W2070531269 abstract "Effective agents with a favorable toxicity profile are needed for women with advanced ovarian cancer. PEGylated liposomal doxorubicin (PLD) is safe and effective as monotherapy for advanced ovarian cancer. It was compared with topotecan in a large Phase III trial in this patient population and was found to be associated with less severe adverse events. In platinum-sensitive patients, PLD was associated with a statistically significant survival advantage over topotecan. PLD is currently under further investigation to expand its role in the treatment of ovarian cancer into combination regimens with carboplatin as first-line treatment, as maintenance therapy as a single-agent, and in combination with molecularly targeted agents in the salvage setting." @default.
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• W2070531269 date "2008-01-01" @default.
• W2070531269 modified "2023-10-16" @default.
• W2070531269 title "PEGylated liposomal doxorubicin: present and future role in the treatment of ovarian cancer" @default.
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• W2070531269 doi "https://doi.org/10.1586/17474108.3.1.21" @default.
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