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- W2070563470 abstract "Abstract We investigated the effects of genetic counseling given before amniocentesis that is given based on maternal serum screening (using the cut-off value of 1/250) and genetic sonogram results (± abnormal ultrasound marker) on pregnant women who are 35 years and older age. Their attitudes towards amniocentesis after genetic counseling were evaluated. Among 340 women, 223 (65.6%) were in the high-risk group and 117 (34.4%) were in the low-risk group according to non-invasive test results. After counseling, 216 pregnant women (167 cases have high-risk, 49 cases who had low-risk) decided to have amniocentesis while 124 women (56 with high-risk and 68 with low-risk) declined it. Fourteen abnormal karyotypes were detected. All pregnant women who had fetuses with chromosomal aberrations were in high-risk group. Our study shows that screening by non-invasive prenatal diagnostic tool has an effect on families’ choice of amniocentesis. The use of these test results during counseling decreased the number of amniocentesis in a ratio of 36.5%." @default.
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- W2070563470 date "2004-11-26" @default.
- W2070563470 modified "2023-10-18" @default.
- W2070563470 title "The role of genetic counseling on decisions of pregnant women aged 35 years or over regarding amniocentesis in Turkey" @default.
- W2070563470 doi "https://doi.org/10.1016/j.anngen.2004.10.005" @default.
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