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• W2070565915 endingPage "363" @default.
• W2070565915 startingPage "352" @default.
• W2070565915 abstract "Lysosomal storage diseases occur due to incomplete metabolic degradation of macromolecules by various hydrolytic enzymes in the lysosome. Despite structural differences, most of the lysosomal enzymes share many common features including a lysosomal targeting motif and phosphotransferase recognition sites. β-Glucuronidase (GUSB) is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan. The deficiency of GUSB causes mucopolysaccharidosis type VII (MPSVII), leading to lysosomal storage in the brain. GUSB is a well-studied protein for its expression, sequence, structure, and function. The purpose of this review is to summarize our current understanding of sequence, structure, function, and evolution of GUSB and its lysosomal enzyme targeting. Enzyme replacement therapy reported for this protein is also discussed." @default.
• W2070565915 created "2016-06-24" @default.
• W2070565915 creator A5018928127 @default.
• W2070565915 creator A5021941753 @default.
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• W2070565915 creator A5066278286 @default.
• W2070565915 creator A5071547468 @default.
• W2070565915 creator A5077513922 @default.
• W2070565915 date "2013-10-01" @default.
• W2070565915 modified "2023-10-17" @default.
• W2070565915 title "Human<i>β</i>-Glucuronidase: Structure, Function, and Application in Enzyme Replacement Therapy" @default.
• W2070565915 cites W1487662743 @default.
• W2070565915 cites W1506464766 @default.
• W2070565915 cites W1510249550 @default.
• W2070565915 cites W1511267677 @default.
• W2070565915 cites W1516890768 @default.
• W2070565915 cites W1530694445 @default.
• W2070565915 cites W1539503448 @default.
• W2070565915 cites W1554299549 @default.
• W2070565915 cites W1576577451 @default.
• W2070565915 cites W1605271364 @default.
• W2070565915 cites W1668646263 @default.
• W2070565915 cites W1669152149 @default.
• W2070565915 cites W1674289580 @default.
• W2070565915 cites W1786536704 @default.
• W2070565915 cites W183309337 @default.
• W2070565915 cites W1887708259 @default.
• W2070565915 cites W1901125896 @default.
• W2070565915 cites W1911461077 @default.
• W2070565915 cites W1958774730 @default.
• W2070565915 cites W1964136878 @default.
• W2070565915 cites W1968649790 @default.
• W2070565915 cites W1969713014 @default.
• W2070565915 cites W1970030078 @default.
• W2070565915 cites W1970411130 @default.
• W2070565915 cites W1971079101 @default.
• W2070565915 cites W1973470144 @default.
• W2070565915 cites W1974491241 @default.
• W2070565915 cites W1975654543 @default.
• W2070565915 cites W1976017519 @default.
• W2070565915 cites W1978862919 @default.
• W2070565915 cites W1980269923 @default.
• W2070565915 cites W1980909118 @default.
• W2070565915 cites W1980912452 @default.
• W2070565915 cites W1981638195 @default.
• W2070565915 cites W1985031701 @default.
• W2070565915 cites W1988859034 @default.
• W2070565915 cites W1992362792 @default.
• W2070565915 cites W1993439119 @default.
• W2070565915 cites W1996706043 @default.
• W2070565915 cites W1999710020 @default.
• W2070565915 cites W1999953288 @default.
• W2070565915 cites W2001526397 @default.
• W2070565915 cites W2003075241 @default.
• W2070565915 cites W2009175543 @default.
• W2070565915 cites W2009504318 @default.
• W2070565915 cites W2011078702 @default.
• W2070565915 cites W2011729980 @default.
• W2070565915 cites W2014363634 @default.
• W2070565915 cites W2016390889 @default.
• W2070565915 cites W2018139041 @default.
• W2070565915 cites W2019269117 @default.
• W2070565915 cites W2025093370 @default.
• W2070565915 cites W2026324976 @default.
• W2070565915 cites W2027832018 @default.
• W2070565915 cites W2028147489 @default.
• W2070565915 cites W2028533348 @default.
• W2070565915 cites W2030202214 @default.
• W2070565915 cites W2030936467 @default.
• W2070565915 cites W2033269583 @default.
• W2070565915 cites W2033749895 @default.
• W2070565915 cites W2034450106 @default.
• W2070565915 cites W2038649031 @default.
• W2070565915 cites W2040353333 @default.
• W2070565915 cites W2040714145 @default.
• W2070565915 cites W2041030586 @default.
• W2070565915 cites W2042509708 @default.
• W2070565915 cites W2044380365 @default.
• W2070565915 cites W2045739126 @default.
• W2070565915 cites W2050897591 @default.
• W2070565915 cites W2053161351 @default.
• W2070565915 cites W2055792884 @default.
• W2070565915 cites W2057545775 @default.
• W2070565915 cites W2058217076 @default.
• W2070565915 cites W2059243802 @default.
• W2070565915 cites W2060341674 @default.
• W2070565915 cites W2060361930 @default.
• W2070565915 cites W2062611561 @default.
• W2070565915 cites W2062739018 @default.
• W2070565915 cites W2062963785 @default.
• W2070565915 cites W2064240900 @default.
• W2070565915 cites W2067515443 @default.
• W2070565915 cites W2068348418 @default.
• W2070565915 cites W2069274491 @default.
• W2070565915 cites W2070258487 @default.
• W2070565915 cites W2070981327 @default.
• W2070565915 cites W2072924153 @default.
• W2070565915 cites W2074396031 @default.

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