Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070569857> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2070569857 endingPage "947" @default.
- W2070569857 startingPage "943" @default.
- W2070569857 abstract "We have developed enzyme-linked immunoassays (ELISAs) that measure major proteins that are associated with pulmonary surfactant. Using these ELISAs, we tested sequential tracheal aspirates from infants severely ill with respiratory distress syndrome (RDS) who had been treated either with exogenous surfactant or with placebo within 8 h of birth. On average, we found low concentrations of surfactant proteins in tracheal aspirates on Day 1 of life, with increases evident by Day 3. The surfactant used in this study (TA surfactant) contains only the low molecular weight (6 kDa) surfactant proteins and not the 35 kDa surfactant protein. As we expected, those who were treated with TA surfactant more frequently had detectable concentrations of low molecular weight surfactant protein on the second day of life when compared with control infants. No differences were evident in the concentrations of surfactant proteins between the 2 groups by Day 3, nor were differences evident between the 2 groups evident for 35 kDa surfactant protein during the first 3 days of life. Increased low molecular weight surfactant proteins in tracheal aspirates 1 to 2 days after surfactant therapy may occur either because of persistence of exogenous surfactant proteins and/or enhanced surfactant protein production. Comparisons with measurements from other groups of patients with RDS confirm that absence of both surfactant proteins reflects alveolar surfactant deficiency." @default.
- W2070569857 created "2016-06-24" @default.
- W2070569857 creator A5001776155 @default.
- W2070569857 creator A5025413774 @default.
- W2070569857 creator A5026008537 @default.
- W2070569857 creator A5045307901 @default.
- W2070569857 creator A5067848052 @default.
- W2070569857 creator A5086833930 @default.
- W2070569857 date "1988-04-01" @default.
- W2070569857 modified "2023-10-16" @default.
- W2070569857 title "Surfactant-associated Proteins in Tracheal Aspirates of Infants with Respiratory Distress Syndrome after Surfactant Therapy" @default.
- W2070569857 cites W1548692828 @default.
- W2070569857 cites W1586315850 @default.
- W2070569857 cites W1590712626 @default.
- W2070569857 cites W1993335885 @default.
- W2070569857 cites W2004176673 @default.
- W2070569857 cites W2014321075 @default.
- W2070569857 cites W2034499823 @default.
- W2070569857 cites W2070692934 @default.
- W2070569857 cites W2074670609 @default.
- W2070569857 cites W2081202307 @default.
- W2070569857 cites W2093178095 @default.
- W2070569857 cites W4293247451 @default.
- W2070569857 doi "https://doi.org/10.1164/ajrccm/137.4.943" @default.
- W2070569857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3355003" @default.
- W2070569857 hasPublicationYear "1988" @default.
- W2070569857 type Work @default.
- W2070569857 sameAs 2070569857 @default.
- W2070569857 citedByCount "41" @default.
- W2070569857 countsByYear W20705698572012 @default.
- W2070569857 countsByYear W20705698572014 @default.
- W2070569857 countsByYear W20705698572020 @default.
- W2070569857 crossrefType "journal-article" @default.
- W2070569857 hasAuthorship W2070569857A5001776155 @default.
- W2070569857 hasAuthorship W2070569857A5025413774 @default.
- W2070569857 hasAuthorship W2070569857A5026008537 @default.
- W2070569857 hasAuthorship W2070569857A5045307901 @default.
- W2070569857 hasAuthorship W2070569857A5067848052 @default.
- W2070569857 hasAuthorship W2070569857A5086833930 @default.
- W2070569857 hasConcept C126322002 @default.
- W2070569857 hasConcept C141071460 @default.
- W2070569857 hasConcept C141983124 @default.
- W2070569857 hasConcept C185592680 @default.
- W2070569857 hasConcept C194108754 @default.
- W2070569857 hasConcept C203014093 @default.
- W2070569857 hasConcept C2776953283 @default.
- W2070569857 hasConcept C2778376644 @default.
- W2070569857 hasConcept C2779234561 @default.
- W2070569857 hasConcept C2780395437 @default.
- W2070569857 hasConcept C534529494 @default.
- W2070569857 hasConcept C54355233 @default.
- W2070569857 hasConcept C55493867 @default.
- W2070569857 hasConcept C58226133 @default.
- W2070569857 hasConcept C71924100 @default.
- W2070569857 hasConcept C86803240 @default.
- W2070569857 hasConceptScore W2070569857C126322002 @default.
- W2070569857 hasConceptScore W2070569857C141071460 @default.
- W2070569857 hasConceptScore W2070569857C141983124 @default.
- W2070569857 hasConceptScore W2070569857C185592680 @default.
- W2070569857 hasConceptScore W2070569857C194108754 @default.
- W2070569857 hasConceptScore W2070569857C203014093 @default.
- W2070569857 hasConceptScore W2070569857C2776953283 @default.
- W2070569857 hasConceptScore W2070569857C2778376644 @default.
- W2070569857 hasConceptScore W2070569857C2779234561 @default.
- W2070569857 hasConceptScore W2070569857C2780395437 @default.
- W2070569857 hasConceptScore W2070569857C534529494 @default.
- W2070569857 hasConceptScore W2070569857C54355233 @default.
- W2070569857 hasConceptScore W2070569857C55493867 @default.
- W2070569857 hasConceptScore W2070569857C58226133 @default.
- W2070569857 hasConceptScore W2070569857C71924100 @default.
- W2070569857 hasConceptScore W2070569857C86803240 @default.
- W2070569857 hasIssue "4" @default.
- W2070569857 hasLocation W20705698571 @default.
- W2070569857 hasLocation W20705698572 @default.
- W2070569857 hasOpenAccess W2070569857 @default.
- W2070569857 hasPrimaryLocation W20705698571 @default.
- W2070569857 hasRelatedWork W1522502345 @default.
- W2070569857 hasRelatedWork W1989391504 @default.
- W2070569857 hasRelatedWork W2008806262 @default.
- W2070569857 hasRelatedWork W2024689261 @default.
- W2070569857 hasRelatedWork W2024958896 @default.
- W2070569857 hasRelatedWork W2070569857 @default.
- W2070569857 hasRelatedWork W2099469033 @default.
- W2070569857 hasRelatedWork W2397652243 @default.
- W2070569857 hasRelatedWork W2404793792 @default.
- W2070569857 hasRelatedWork W2489460955 @default.
- W2070569857 hasVolume "137" @default.
- W2070569857 isParatext "false" @default.
- W2070569857 isRetracted "false" @default.
- W2070569857 magId "2070569857" @default.
- W2070569857 workType "article" @default.