Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070611665> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2070611665 endingPage "684" @default.
- W2070611665 startingPage "679" @default.
- W2070611665 abstract "Glial activation and degeneration are important outcomes in the pathophysiology of acute brain and spinal cord injury (SCI). Our main goal was to investigate the pattern of glial activation and degeneration during secondary degeneration in both gray matter (GM) and white matter (WM) following SCI. Adult rats were deeply anesthetized and injected with 20 nmol of N-methyl-d-aspartate (NMDA) into the ventral horn of rat spinal cord (SC) on T7. Animals were perfused after survival times of 1, 3, and 7 days. Ten-micrometer sections were submitted to immunocytochemistry for activated macrophages/microglia, astrocytes, oligodendrocytes, and myelin. Astrocyte activation was more intense in the vacuolated white matter than in gray matter and was first noticed in this former region. Microglial activation was more intense in the gray matter and was clear by 24 h following NMDA injection. Both astrocytosis and microglial activation were more intense in the later survival times. Conspicuous WM vacuolation was present mainly at the 3-day survival time and decreased by 7 days after the primary damage. Quantitative analysis revealed an increase in the number of pyknotic bodies mainly at the 7-day survival time in both ventral and lateral white matter. These pyknotic bodies were frequently found inside white matter vacuoles like for degenerating oligodendrocytes. These results suggest a differential pattern of astrocytosis and microglia activation for white and gray matter following SCI. This phenomenon can be related to the different pathological outcomes for this two SC regions following acute injury." @default.
- W2070611665 created "2016-06-24" @default.
- W2070611665 creator A5006437655 @default.
- W2070611665 creator A5054737133 @default.
- W2070611665 creator A5057865874 @default.
- W2070611665 date "1982-05-01" @default.
- W2070611665 modified "2023-09-26" @default.
- W2070611665 title "Myelin-associated glycoprotein localized immunocytochemically in periaxonal regions of oligodendroglia during hexachlorophene intoxication" @default.
- W2070611665 cites W123941527 @default.
- W2070611665 cites W1971284849 @default.
- W2070611665 cites W1973939197 @default.
- W2070611665 cites W1981040573 @default.
- W2070611665 cites W1992532568 @default.
- W2070611665 cites W2011138394 @default.
- W2070611665 cites W2032552530 @default.
- W2070611665 cites W2034088005 @default.
- W2070611665 cites W2047025292 @default.
- W2070611665 cites W2064183906 @default.
- W2070611665 cites W2072841951 @default.
- W2070611665 cites W2080001188 @default.
- W2070611665 cites W2110662341 @default.
- W2070611665 cites W2122283078 @default.
- W2070611665 cites W2133273981 @default.
- W2070611665 cites W2331508605 @default.
- W2070611665 cites W1992316414 @default.
- W2070611665 doi "https://doi.org/10.1016/0006-8993(82)90550-9" @default.
- W2070611665 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6178473" @default.
- W2070611665 hasPublicationYear "1982" @default.
- W2070611665 type Work @default.
- W2070611665 sameAs 2070611665 @default.
- W2070611665 citedByCount "22" @default.
- W2070611665 crossrefType "journal-article" @default.
- W2070611665 hasAuthorship W2070611665A5006437655 @default.
- W2070611665 hasAuthorship W2070611665A5054737133 @default.
- W2070611665 hasAuthorship W2070611665A5057865874 @default.
- W2070611665 hasConcept C105702510 @default.
- W2070611665 hasConcept C126838900 @default.
- W2070611665 hasConcept C142724271 @default.
- W2070611665 hasConcept C143409427 @default.
- W2070611665 hasConcept C169760540 @default.
- W2070611665 hasConcept C203014093 @default.
- W2070611665 hasConcept C2776914184 @default.
- W2070611665 hasConcept C2777542381 @default.
- W2070611665 hasConcept C2777682930 @default.
- W2070611665 hasConcept C2778609137 @default.
- W2070611665 hasConcept C2779830541 @default.
- W2070611665 hasConcept C2780775167 @default.
- W2070611665 hasConcept C2781192897 @default.
- W2070611665 hasConcept C2908656565 @default.
- W2070611665 hasConcept C529278444 @default.
- W2070611665 hasConcept C71924100 @default.
- W2070611665 hasConcept C86803240 @default.
- W2070611665 hasConceptScore W2070611665C105702510 @default.
- W2070611665 hasConceptScore W2070611665C126838900 @default.
- W2070611665 hasConceptScore W2070611665C142724271 @default.
- W2070611665 hasConceptScore W2070611665C143409427 @default.
- W2070611665 hasConceptScore W2070611665C169760540 @default.
- W2070611665 hasConceptScore W2070611665C203014093 @default.
- W2070611665 hasConceptScore W2070611665C2776914184 @default.
- W2070611665 hasConceptScore W2070611665C2777542381 @default.
- W2070611665 hasConceptScore W2070611665C2777682930 @default.
- W2070611665 hasConceptScore W2070611665C2778609137 @default.
- W2070611665 hasConceptScore W2070611665C2779830541 @default.
- W2070611665 hasConceptScore W2070611665C2780775167 @default.
- W2070611665 hasConceptScore W2070611665C2781192897 @default.
- W2070611665 hasConceptScore W2070611665C2908656565 @default.
- W2070611665 hasConceptScore W2070611665C529278444 @default.
- W2070611665 hasConceptScore W2070611665C71924100 @default.
- W2070611665 hasConceptScore W2070611665C86803240 @default.
- W2070611665 hasIssue "2" @default.
- W2070611665 hasLocation W20706116651 @default.
- W2070611665 hasLocation W20706116652 @default.
- W2070611665 hasOpenAccess W2070611665 @default.
- W2070611665 hasPrimaryLocation W20706116651 @default.
- W2070611665 hasRelatedWork W1983702345 @default.
- W2070611665 hasRelatedWork W1988586000 @default.
- W2070611665 hasRelatedWork W2004130834 @default.
- W2070611665 hasRelatedWork W2069350223 @default.
- W2070611665 hasRelatedWork W2133766206 @default.
- W2070611665 hasRelatedWork W2157486029 @default.
- W2070611665 hasRelatedWork W2184607260 @default.
- W2070611665 hasRelatedWork W2341139697 @default.
- W2070611665 hasRelatedWork W3122769134 @default.
- W2070611665 hasRelatedWork W2181303350 @default.
- W2070611665 hasVolume "239" @default.
- W2070611665 isParatext "false" @default.
- W2070611665 isRetracted "false" @default.
- W2070611665 magId "2070611665" @default.
- W2070611665 workType "article" @default.