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- W2070657162 abstract "The dipeptide gamma-l-glutamyl-l-phenylalanine (γ-glu-phe) has been identified as a major biosynthetic product of the larva of the housefly Musca domestica L. The concentration of γ-glu-phe increases continually during larval growth, reaching a maximum of 13·9 μM/g wet wt. in the fully grown larva. More than 85 per cent of the dipeptide is found in the blood at this time. During the first few hours after the onset of hardening and darkening of the puparium, the level of γ-glu-phe falls markedly. After 8 hr of tanning virtually no trace of dipeptide can be found. The disappearance of γ-glu-phe is under the control of the moulting hormone ecdysone as shown by ligature experiments. Gamma-glu-phe may play a key rôle in puparium formation in the housefly by providing a large phenylalanine reservoir which can be metabolized to melanins and/or quinones for tanning cuticle proteins during sclerotization. Occurrence of γ-glu-phe appears to be restricted to the larva of flies of the genus Musca. No good a priori reason can be given for its biosynthesis by members of this genus." @default.
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- W2070657162 date "1970-05-01" @default.
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- W2070657162 title "Biosynthesis of gamma-l-glutamyl-l-phenylalanine by the larva of the housefly Musca domestica" @default.
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- W2070657162 doi "https://doi.org/10.1016/0022-1910(70)90222-2" @default.
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