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- W2070668841 abstract "Tadpoles of Bufo vulgaris formosus were kept in a 0.05% thiourea solution for 87 days, and the effects on the eye-balls, thyroid glands and gonads were histologically examind.Exophthalmos produced by a striking enlargement of the eye-ball was observed in different degrees in the majority of the treated tadpoles. The thyroid glands of those tadpoles remarkably increased in size, and grew into Struma parenchymatosa.Gonadal differentiation was more advanced as compared with the frogs of the same age collected in the field, although degenerative changes were observed in the ovaries of some tadpoles. Development of Bidder's organ was considerably inhibited. Sex ratio was 1:1 as a whole, although severe exophthalmos was mostly observed in females.Masculinization of the genetic female following treatments with goitrogens seems to occur easily only in higher anurans such as Rana and Rhacophcrus, and such a reversal seems to be difficult to occur in urodeles and lower anurans." @default.
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- W2070668841 date "1959-01-01" @default.
- W2070668841 modified "2023-09-25" @default.
- W2070668841 title "PECULIAR RESPONSE OF TOAD LARVAE TO THIOUREA TREATMENT" @default.
- W2070668841 cites W2000522136 @default.
- W2070668841 doi "https://doi.org/10.1507/endocrj1954.6.183" @default.
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