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• W2070672521 abstract "In the past two decades, research has underlined the potential of ultrasound and microbubbles to enhance drug delivery. However, there is less consensus on the biophysical and biological mechanisms leading to this enhanced delivery. Sonoporation, i.e. the formation of temporary pores in the cell membrane, as well as enhanced endocytosis is reported. Because of the variety of ultrasound settings used and corresponding microbubble behavior, a clear overview is missing. Therefore, in this review, the mechanisms contributing to sonoporation are categorized according to three ultrasound settings: i) low intensity ultrasound leading to stable cavitation of microbubbles, ii) high intensity ultrasound leading to inertial cavitation with microbubble collapse, and iii) ultrasound application in the absence of microbubbles. Using low intensity ultrasound, the endocytotic uptake of several drugs could be stimulated, while short but intense ultrasound pulses can be applied to induce pore formation and the direct cytoplasmic uptake of drugs. Ultrasound intensities may be adapted to create pore sizes correlating with drug size. Small molecules are able to diffuse passively through small pores created by low intensity ultrasound treatment. However, delivery of larger drugs such as nanoparticles and gene complexes, will require higher ultrasound intensities in order to allow direct cytoplasmic entry." @default.
• W2070672521 created "2016-06-24" @default.
• W2070672521 creator A5010359444 @default.
• W2070672521 creator A5030125329 @default.
• W2070672521 creator A5047269869 @default.
• W2070672521 creator A5052529308 @default.
• W2070672521 creator A5085530826 @default.
• W2070672521 date "2014-06-01" @default.
• W2070672521 modified "2023-10-10" @default.
• W2070672521 title "Understanding ultrasound induced sonoporation: Definitions and underlying mechanisms" @default.
• W2070672521 cites W1595583688 @default.
• W2070672521 cites W1605708617 @default.
• W2070672521 cites W1862606445 @default.
• W2070672521 cites W1892231821 @default.
• W2070672521 cites W1918495273 @default.
• W2070672521 cites W1936770188 @default.
• W2070672521 cites W1946056901 @default.
• W2070672521 cites W1964630494 @default.
• W2070672521 cites W1964767370 @default.
• W2070672521 cites W1966156756 @default.
• W2070672521 cites W1967776587 @default.
• W2070672521 cites W1968403808 @default.
• W2070672521 cites W1969786757 @default.
• W2070672521 cites W1971119618 @default.
• W2070672521 cites W1971499045 @default.
• W2070672521 cites W1972788857 @default.
• W2070672521 cites W1973929456 @default.
• W2070672521 cites W1975798006 @default.
• W2070672521 cites W1976239373 @default.
• W2070672521 cites W1977105937 @default.
• W2070672521 cites W1977891925 @default.
• W2070672521 cites W1984976020 @default.
• W2070672521 cites W1988150044 @default.
• W2070672521 cites W1989569827 @default.
• W2070672521 cites W1993471191 @default.
• W2070672521 cites W1994684658 @default.
• W2070672521 cites W1995191681 @default.
• W2070672521 cites W1995873025 @default.
• W2070672521 cites W1998476547 @default.
• W2070672521 cites W2000573877 @default.
• W2070672521 cites W2000871024 @default.
• W2070672521 cites W2001245960 @default.
• W2070672521 cites W2001455415 @default.
• W2070672521 cites W2002553504 @default.
• W2070672521 cites W2002936944 @default.
• W2070672521 cites W2004212352 @default.
• W2070672521 cites W2006525925 @default.
• W2070672521 cites W2012884556 @default.
• W2070672521 cites W2013294072 @default.
• W2070672521 cites W2013593131 @default.
• W2070672521 cites W2013844718 @default.
• W2070672521 cites W2014770379 @default.
• W2070672521 cites W2021092582 @default.
• W2070672521 cites W2021140900 @default.
• W2070672521 cites W2021156560 @default.
• W2070672521 cites W2021275436 @default.
• W2070672521 cites W2022927172 @default.
• W2070672521 cites W2023713300 @default.
• W2070672521 cites W2024072689 @default.
• W2070672521 cites W2024147018 @default.
• W2070672521 cites W2026988376 @default.
• W2070672521 cites W2029765361 @default.
• W2070672521 cites W2029994399 @default.
• W2070672521 cites W2032931290 @default.
• W2070672521 cites W2034330513 @default.
• W2070672521 cites W2035244308 @default.
• W2070672521 cites W2036203675 @default.
• W2070672521 cites W2037307064 @default.
• W2070672521 cites W2039167592 @default.
• W2070672521 cites W2039411165 @default.
• W2070672521 cites W2040687198 @default.
• W2070672521 cites W2040998173 @default.
• W2070672521 cites W2042208918 @default.
• W2070672521 cites W2043861960 @default.
• W2070672521 cites W2044266448 @default.
• W2070672521 cites W2045190338 @default.
• W2070672521 cites W2048554067 @default.
• W2070672521 cites W2050839806 @default.
• W2070672521 cites W2051474419 @default.
• W2070672521 cites W2055492146 @default.
• W2070672521 cites W2055859759 @default.
• W2070672521 cites W2056360581 @default.
• W2070672521 cites W2057335942 @default.
• W2070672521 cites W2058692508 @default.
• W2070672521 cites W2059378639 @default.
• W2070672521 cites W2060592071 @default.
• W2070672521 cites W2060736183 @default.
• W2070672521 cites W2061206693 @default.
• W2070672521 cites W2065001189 @default.
• W2070672521 cites W2070112477 @default.
• W2070672521 cites W2070414574 @default.
• W2070672521 cites W2072917407 @default.
• W2070672521 cites W2073210322 @default.
• W2070672521 cites W2073515640 @default.
• W2070672521 cites W2074429564 @default.
• W2070672521 cites W2075989250 @default.
• W2070672521 cites W2078464847 @default.
• W2070672521 cites W2081223913 @default.

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