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- W2070683670 abstract "Serum immunoreactive insulin levels (IRI) and insulin sensitivity were studied in lean, genetically obese “fatty” rats, and rats that became obese following hypothalamic lesions. Serum IRI was increased in obese “fatty” rats at 6 wk, 4 mo, and 11 mo of age. Similar increases were observed in hypothalamic lesioned (HTL) obese rats. Histologic changes in the appearance of islet tissue were described. Insulin sensitivity was studied in both “fatty” and HTL rats after a 19-hr fast. Genetic, but not regulatory, obesity was accompanied by insulin resistance. Possible reasons for this difference are discussed." @default.
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- W2070683670 title "Hyperinsulinemia and insulin resistance in genetically obese rats" @default.
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- W2070683670 doi "https://doi.org/10.1016/0026-0495(72)90070-4" @default.
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