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- W2070684401 endingPage "17185" @default.
- W2070684401 startingPage "17180" @default.
- W2070684401 abstract "Stress is a state of the mind, involving both brain and body as well as their interactions; it differs among individuals and reflects not only major life events but also the conflicts and pressures of daily life that alter physiological systems to produce a chronic stress burden that, in turn, is a factor in the expression of disease. This burden reflects the impact of not only life experiences but also genetic variations and individual health behaviors such as diet, physical activity, sleep, and substance abuse; it also reflects stable epigenetic modifications in development that set lifelong patterns of physiological reactivity and behavior through biological embedding of early environments interacting with cumulative change from experiences over the lifespan. Hormones associated with the chronic stress burden protect the body in the short run and promote adaptation (allostasis), but in the long run, the burden of chronic stress causes changes in the brain and body that can lead to disease (allostatic load and overload). Brain circuits are plastic and remodeled by stress to change the balance between anxiety, mood control, memory, and decision making. Such changes may have adaptive value in particular contexts, but their persistence and lack of reversibility can be maladaptive. However, the capacity of brain plasticity to effects of stressful experiences in adult life has only begun to be explored along with the efficacy of top-down strategies for helping the brain change itself, sometimes aided by pharmaceutical agents and other treatments." @default.
- W2070684401 created "2016-06-24" @default.
- W2070684401 creator A5035103174 @default.
- W2070684401 date "2012-10-08" @default.
- W2070684401 modified "2023-10-17" @default.
- W2070684401 title "Brain on stress: How the social environment gets under the skin" @default.
- W2070684401 cites W1527534059 @default.
- W2070684401 cites W1566981583 @default.
- W2070684401 cites W1619226291 @default.
- W2070684401 cites W1964518559 @default.
- W2070684401 cites W1969289932 @default.
- W2070684401 cites W1972072960 @default.
- W2070684401 cites W1976320699 @default.
- W2070684401 cites W1977143695 @default.
- W2070684401 cites W1977774953 @default.
- W2070684401 cites W1980249174 @default.
- W2070684401 cites W1981748148 @default.
- W2070684401 cites W1984427714 @default.
- W2070684401 cites W1984959581 @default.
- W2070684401 cites W1987528796 @default.
- W2070684401 cites W1988993555 @default.
- W2070684401 cites W1989924524 @default.
- W2070684401 cites W1991948487 @default.
- W2070684401 cites W1993241875 @default.
- W2070684401 cites W1993713289 @default.
- W2070684401 cites W1997221050 @default.
- W2070684401 cites W1997961959 @default.
- W2070684401 cites W2006387633 @default.
- W2070684401 cites W2008050722 @default.
- W2070684401 cites W2009782994 @default.
- W2070684401 cites W2010397126 @default.
- W2070684401 cites W2012130547 @default.
- W2070684401 cites W2013360275 @default.
- W2070684401 cites W2021030890 @default.
- W2070684401 cites W2022221011 @default.
- W2070684401 cites W2025468569 @default.
- W2070684401 cites W2026179327 @default.
- W2070684401 cites W2026328830 @default.
- W2070684401 cites W2027061276 @default.
- W2070684401 cites W2027368063 @default.
- W2070684401 cites W2030265072 @default.
- W2070684401 cites W2035384914 @default.
- W2070684401 cites W2036814814 @default.
- W2070684401 cites W2037043502 @default.
- W2070684401 cites W2038103586 @default.
- W2070684401 cites W2043990776 @default.
- W2070684401 cites W2044710410 @default.
- W2070684401 cites W2044998035 @default.
- W2070684401 cites W2045013563 @default.
- W2070684401 cites W2050582843 @default.
- W2070684401 cites W2051423370 @default.
- W2070684401 cites W2051715358 @default.
- W2070684401 cites W2054980594 @default.
- W2070684401 cites W2055621916 @default.
- W2070684401 cites W2056065044 @default.
- W2070684401 cites W2058176183 @default.
- W2070684401 cites W2062804578 @default.
- W2070684401 cites W2062975372 @default.
- W2070684401 cites W2068122778 @default.
- W2070684401 cites W2069247119 @default.
- W2070684401 cites W2069368135 @default.
- W2070684401 cites W2069810154 @default.
- W2070684401 cites W2071663677 @default.
- W2070684401 cites W2071831557 @default.
- W2070684401 cites W2072139179 @default.
- W2070684401 cites W2072546823 @default.
- W2070684401 cites W2076764419 @default.
- W2070684401 cites W2080576899 @default.
- W2070684401 cites W2084207424 @default.
- W2070684401 cites W2084246956 @default.
- W2070684401 cites W2084499621 @default.
- W2070684401 cites W2087053296 @default.
- W2070684401 cites W2087368034 @default.
- W2070684401 cites W2087477534 @default.
- W2070684401 cites W2087955490 @default.
- W2070684401 cites W2088719746 @default.
- W2070684401 cites W2089198034 @default.
- W2070684401 cites W2093320992 @default.
- W2070684401 cites W2094097475 @default.
- W2070684401 cites W2100561031 @default.
- W2070684401 cites W2100745738 @default.
- W2070684401 cites W2102685543 @default.
- W2070684401 cites W2104417544 @default.
- W2070684401 cites W2105489250 @default.
- W2070684401 cites W2107423916 @default.
- W2070684401 cites W2108025392 @default.
- W2070684401 cites W2110141182 @default.
- W2070684401 cites W2116769635 @default.
- W2070684401 cites W2120743339 @default.
- W2070684401 cites W2129030266 @default.
- W2070684401 cites W2129597363 @default.
- W2070684401 cites W2132539548 @default.
- W2070684401 cites W2134083528 @default.
- W2070684401 cites W2136403062 @default.
- W2070684401 cites W2139681269 @default.
- W2070684401 cites W2142771923 @default.
- W2070684401 cites W2144101679 @default.
- W2070684401 cites W2144789364 @default.