FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070701656> ?p ?o ?g. }

• W2070701656 endingPage "1279" @default.
• W2070701656 startingPage "1272" @default.
• W2070701656 abstract "This study aimed to investigate the effect of magnolol (5,5′-diallyl-2,2′-biphenyldiol) on contraction in distal colonic segments of rats and the underlying mechanisms. Colonic segments were mounted in organ baths for isometric force measurement. Whole-cell voltage-sensitive L-type Ca2+ currents were recorded on isolated single colonic smooth muscle cells using patch-clamp technique. The spontaneous contractions and acetylcholine (ACh)- and Bay K 8644-induced contractions were inhibited by magnolol (3–100 μM). In the presence of Bay K8644 (100 nM), magnolol (10–100 μM) inhibited the contraction induced by 10 μM ACh. By contrast, tetrodotoxin (100 nM) and Nώ-nitro-l-arginine methyl ester (l-NAME 100 μM) did not change the inhibitory effect of magnolol (10 μM). In addition, magnolol (3–100 μM) inhibited the L-type Ca2+ currents. The present results suggest that magnolol inhibits colonic smooth muscle contraction through downregulating L-type Ca2+ channel activity." @default.
• W2070701656 created "2016-06-24" @default.
• W2070701656 creator A5012364107 @default.
• W2070701656 creator A5020934796 @default.
• W2070701656 creator A5021520609 @default.
• W2070701656 creator A5022248804 @default.
• W2070701656 creator A5049274840 @default.
• W2070701656 creator A5049761195 @default.
• W2070701656 creator A5052949240 @default.
• W2070701656 creator A5071329338 @default.
• W2070701656 creator A5073865035 @default.
• W2070701656 creator A5074425597 @default.
• W2070701656 creator A5086030076 @default.
• W2070701656 creator A5086342255 @default.
• W2070701656 date "2013-11-01" @default.
• W2070701656 modified "2023-09-26" @default.
• W2070701656 title "Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats" @default.
• W2070701656 cites W1491256154 @default.
• W2070701656 cites W1970975883 @default.
• W2070701656 cites W1988725623 @default.
• W2070701656 cites W2001697686 @default.
• W2070701656 cites W2003004088 @default.
• W2070701656 cites W2033131416 @default.
• W2070701656 cites W2056538369 @default.
• W2070701656 cites W2057106831 @default.
• W2070701656 cites W2074990507 @default.
• W2070701656 cites W2088764363 @default.
• W2070701656 cites W2098585537 @default.
• W2070701656 cites W2099334963 @default.
• W2070701656 cites W2124569729 @default.
• W2070701656 cites W2142731996 @default.
• W2070701656 cites W2147814677 @default.
• W2070701656 cites W2165751253 @default.
• W2070701656 cites W2174059967 @default.
• W2070701656 cites W2419387967 @default.
• W2070701656 doi "https://doi.org/10.1016/j.phymed.2013.07.008" @default.
• W2070701656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23972358" @default.
• W2070701656 hasPublicationYear "2013" @default.
• W2070701656 type Work @default.
• W2070701656 sameAs 2070701656 @default.
• W2070701656 citedByCount "12" @default.
• W2070701656 countsByYear W20707016562014 @default.
• W2070701656 countsByYear W20707016562015 @default.
• W2070701656 countsByYear W20707016562017 @default.
• W2070701656 countsByYear W20707016562018 @default.
• W2070701656 countsByYear W20707016562019 @default.
• W2070701656 countsByYear W20707016562021 @default.
• W2070701656 countsByYear W20707016562022 @default.
• W2070701656 crossrefType "journal-article" @default.
• W2070701656 hasAuthorship W2070701656A5012364107 @default.
• W2070701656 hasAuthorship W2070701656A5020934796 @default.
• W2070701656 hasAuthorship W2070701656A5021520609 @default.
• W2070701656 hasAuthorship W2070701656A5022248804 @default.
• W2070701656 hasAuthorship W2070701656A5049274840 @default.
• W2070701656 hasAuthorship W2070701656A5049761195 @default.
• W2070701656 hasAuthorship W2070701656A5052949240 @default.
• W2070701656 hasAuthorship W2070701656A5071329338 @default.
• W2070701656 hasAuthorship W2070701656A5073865035 @default.
• W2070701656 hasAuthorship W2070701656A5074425597 @default.
• W2070701656 hasAuthorship W2070701656A5086030076 @default.
• W2070701656 hasAuthorship W2070701656A5086342255 @default.
• W2070701656 hasConcept C103486182 @default.
• W2070701656 hasConcept C105702510 @default.
• W2070701656 hasConcept C12554922 @default.
• W2070701656 hasConcept C126322002 @default.
• W2070701656 hasConcept C134018914 @default.
• W2070701656 hasConcept C163415756 @default.
• W2070701656 hasConcept C178790620 @default.
• W2070701656 hasConcept C185592680 @default.
• W2070701656 hasConcept C18699975 @default.
• W2070701656 hasConcept C2775910092 @default.
• W2070701656 hasConcept C2776050358 @default.
• W2070701656 hasConcept C2781009524 @default.
• W2070701656 hasConcept C43617362 @default.
• W2070701656 hasConcept C519063684 @default.
• W2070701656 hasConcept C71924100 @default.
• W2070701656 hasConcept C86803240 @default.
• W2070701656 hasConceptScore W2070701656C103486182 @default.
• W2070701656 hasConceptScore W2070701656C105702510 @default.
• W2070701656 hasConceptScore W2070701656C12554922 @default.
• W2070701656 hasConceptScore W2070701656C126322002 @default.
• W2070701656 hasConceptScore W2070701656C134018914 @default.
• W2070701656 hasConceptScore W2070701656C163415756 @default.
• W2070701656 hasConceptScore W2070701656C178790620 @default.
• W2070701656 hasConceptScore W2070701656C185592680 @default.
• W2070701656 hasConceptScore W2070701656C18699975 @default.
• W2070701656 hasConceptScore W2070701656C2775910092 @default.
• W2070701656 hasConceptScore W2070701656C2776050358 @default.
• W2070701656 hasConceptScore W2070701656C2781009524 @default.
• W2070701656 hasConceptScore W2070701656C43617362 @default.
• W2070701656 hasConceptScore W2070701656C519063684 @default.
• W2070701656 hasConceptScore W2070701656C71924100 @default.
• W2070701656 hasConceptScore W2070701656C86803240 @default.
• W2070701656 hasIssue "14" @default.
• W2070701656 hasLocation W20707016561 @default.
• W2070701656 hasLocation W20707016562 @default.
• W2070701656 hasOpenAccess W2070701656 @default.
• W2070701656 hasPrimaryLocation W20707016561 @default.

• next