Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070709718> ?p ?o ?g. }
- W2070709718 endingPage "18" @default.
- W2070709718 startingPage "12" @default.
- W2070709718 abstract "Severe acute respiratory syndrome (SARS) is caused by infection with SARS-associated coronavirus (CoV). Amino acid residues 450-650 of the spike (S) glycoprotein of SARS-CoV (S450-650) contains dominant epitopes for anti-viral antibodies (Abs) in patient sera.To develop and evaluate an ELISA system for detection of anti-S Abs in patient sera.Express recombinant S450-650 in E. Coli and evaluate the sensitivity and specificity of an ELISA system based on the S450-650 polypeptide.The S450-650-based ELISA detected IgG Abs in 41 out of 51 serum samples from 22 hospitalized patients with probable SARS, a result closely correlated with that obtained with a virus-based ELISA (r = 0.75, k = 0.8). Differential anti-S IgG responses were observed amongst SARS patients. Some of them produced anti-S Abs early during their infection, while others failed to make IgG Abs against the S450-650 polypeptide. None of the serum samples from 100 healthy blood donors was positive in the S450-650-based assay.The S450-650-based ELISA can detect anti-S IgG Abs with high sensitivity and specificity." @default.
- W2070709718 created "2016-06-24" @default.
- W2070709718 creator A5003759585 @default.
- W2070709718 creator A5015575299 @default.
- W2070709718 creator A5019342189 @default.
- W2070709718 creator A5023693252 @default.
- W2070709718 creator A5034168127 @default.
- W2070709718 creator A5041204026 @default.
- W2070709718 creator A5065141144 @default.
- W2070709718 creator A5067895132 @default.
- W2070709718 creator A5081349916 @default.
- W2070709718 date "2005-05-01" @default.
- W2070709718 modified "2023-10-18" @default.
- W2070709718 title "Development and evaluation of an enzyme-linked immunosorbent assay for detection of antibodies against the spike protein of SARS-coronavirus" @default.
- W2070709718 cites W1966238900 @default.
- W2070709718 cites W1975490802 @default.
- W2070709718 cites W1985291129 @default.
- W2070709718 cites W2000615699 @default.
- W2070709718 cites W2025170735 @default.
- W2070709718 cites W2027191557 @default.
- W2070709718 cites W2031014666 @default.
- W2070709718 cites W2039663472 @default.
- W2070709718 cites W2060109277 @default.
- W2070709718 cites W2073682867 @default.
- W2070709718 cites W2079058433 @default.
- W2070709718 cites W2080627364 @default.
- W2070709718 cites W2103167703 @default.
- W2070709718 cites W2116586125 @default.
- W2070709718 cites W2130489595 @default.
- W2070709718 cites W2136039989 @default.
- W2070709718 cites W2137976135 @default.
- W2070709718 cites W2145944641 @default.
- W2070709718 cites W2146476111 @default.
- W2070709718 cites W2158785087 @default.
- W2070709718 cites W2158939655 @default.
- W2070709718 cites W2165176155 @default.
- W2070709718 cites W2169198329 @default.
- W2070709718 doi "https://doi.org/10.1016/j.jcv.2004.09.024" @default.
- W2070709718 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7108335" @default.
- W2070709718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15797360" @default.
- W2070709718 hasPublicationYear "2005" @default.
- W2070709718 type Work @default.
- W2070709718 sameAs 2070709718 @default.
- W2070709718 citedByCount "13" @default.
- W2070709718 countsByYear W20707097182012 @default.
- W2070709718 countsByYear W20707097182020 @default.
- W2070709718 countsByYear W20707097182021 @default.
- W2070709718 countsByYear W20707097182022 @default.
- W2070709718 crossrefType "journal-article" @default.
- W2070709718 hasAuthorship W2070709718A5003759585 @default.
- W2070709718 hasAuthorship W2070709718A5015575299 @default.
- W2070709718 hasAuthorship W2070709718A5019342189 @default.
- W2070709718 hasAuthorship W2070709718A5023693252 @default.
- W2070709718 hasAuthorship W2070709718A5034168127 @default.
- W2070709718 hasAuthorship W2070709718A5041204026 @default.
- W2070709718 hasAuthorship W2070709718A5065141144 @default.
- W2070709718 hasAuthorship W2070709718A5067895132 @default.
- W2070709718 hasAuthorship W2070709718A5081349916 @default.
- W2070709718 hasBestOaLocation W20707097181 @default.
- W2070709718 hasConcept C104317684 @default.
- W2070709718 hasConcept C108625454 @default.
- W2070709718 hasConcept C142724271 @default.
- W2070709718 hasConcept C153911025 @default.
- W2070709718 hasConcept C159047783 @default.
- W2070709718 hasConcept C159654299 @default.
- W2070709718 hasConcept C195616568 @default.
- W2070709718 hasConcept C203014093 @default.
- W2070709718 hasConcept C2522874641 @default.
- W2070709718 hasConcept C2776844884 @default.
- W2070709718 hasConcept C2777648638 @default.
- W2070709718 hasConcept C2779134260 @default.
- W2070709718 hasConcept C2780898057 @default.
- W2070709718 hasConcept C2909509916 @default.
- W2070709718 hasConcept C3007834351 @default.
- W2070709718 hasConcept C3008058167 @default.
- W2070709718 hasConcept C40767141 @default.
- W2070709718 hasConcept C45189115 @default.
- W2070709718 hasConcept C524204448 @default.
- W2070709718 hasConcept C55493867 @default.
- W2070709718 hasConcept C71924100 @default.
- W2070709718 hasConcept C86803240 @default.
- W2070709718 hasConceptScore W2070709718C104317684 @default.
- W2070709718 hasConceptScore W2070709718C108625454 @default.
- W2070709718 hasConceptScore W2070709718C142724271 @default.
- W2070709718 hasConceptScore W2070709718C153911025 @default.
- W2070709718 hasConceptScore W2070709718C159047783 @default.
- W2070709718 hasConceptScore W2070709718C159654299 @default.
- W2070709718 hasConceptScore W2070709718C195616568 @default.
- W2070709718 hasConceptScore W2070709718C203014093 @default.
- W2070709718 hasConceptScore W2070709718C2522874641 @default.
- W2070709718 hasConceptScore W2070709718C2776844884 @default.
- W2070709718 hasConceptScore W2070709718C2777648638 @default.
- W2070709718 hasConceptScore W2070709718C2779134260 @default.
- W2070709718 hasConceptScore W2070709718C2780898057 @default.
- W2070709718 hasConceptScore W2070709718C2909509916 @default.
- W2070709718 hasConceptScore W2070709718C3007834351 @default.
- W2070709718 hasConceptScore W2070709718C3008058167 @default.
- W2070709718 hasConceptScore W2070709718C40767141 @default.