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- W2070731657 abstract "Follicular lymphoma is an indolent lymphoma associated with a relapsing course. Immunization with tumor B cell idiotype (Id; a unique variable region of surface B cell immunoglobulin) may induce humoral and cellular immune response against the tumor. Based on promising results from early phase clinical trials with Id vaccine, three Phase III trials were initiated, which, despite failing to meet their primary end points, still provided a glimmer of optimism. This article describes the clinical development of the Id vaccine against follicular lymphoma, outlines the outcomes of clinical trials and delineates the future prospects for the integration of the idiotype vaccine into follicular lymphoma treatment." @default.
- W2070731657 created "2016-06-24" @default.
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- W2070731657 date "2011-01-01" @default.
- W2070731657 modified "2023-10-16" @default.
- W2070731657 title "Idiotype vaccine strategies for treatment of follicular lymphoma" @default.
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- W2070731657 doi "https://doi.org/10.2217/fon.10.159" @default.
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