FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070733023> ?p ?o ?g. }

• W2070733023 endingPage "3672" @default.
• W2070733023 startingPage "3672" @default.
• W2070733023 abstract "To investigate the expression of ERG, CD34, CD31 (PECAM-1, platelet/endothelial cell adhesion molecule 1) and factor VIII-related antigen (FVIIIRAg) in the diagnosis of hepatic angiosarcoma patients.Patient samples were collected from January 1986 to December 2012 from the People's Liberation Army General Hospital in Beijing, China. We obtained twenty-four samples of hepatic angiosarcoma (HAS) that were confirmed by two pathologist. The samples were the result of three autopsy cases, eight biopsy cases and 13 patients who underwent surgical tumor removal. The HAS cases accounted for 2.23% (24/1075) of all hepatic vascular tumors at the hospital during the same time period. Patient histories including age, gender, clinical manifestations, medical treatments, laboratory tests, radiological images, histological observations and outcomes for each case were analyzed in detail. All samples were evaluated histologically with hematoxylin and eosin staining. Using immunohistochemistry, the expression and localization of ERG was examined in all HAS specimens and compared to the known endothelial markers CD34, CD31 and FVIIIRAg. The endothelial markers were also evaluated in a panel of non-HAS tumors.This cohort of 24 HAS cases is, to the best of our knowledge, currently the largest cohort in the world in the publicly available literature. Hepatic angiosarcoma tissue samples were obtained from 14 males and 10 females with a mean age of 50.6 years (range: 7-86 years). The patients presented with the following clinical manifestations: abdominal pain (16/24), back pain (3/24), heart palpitations (1/20), cough (1/24) or no clinical symptoms (3/24). Tumors were predominantly localized in the right hepatic lobe (15/24) or left hepatic lobe (6/24), or a diffuse growth on the right and left hepatic lobes (3/24). Eleven patients underwent surgical resection (45.8%), two patients received a liver transplant (8.3%), eight patients received interventional therapy (33.3%) and three patients received no treatment (lesions discovered at autopsy, 12.5%). Postoperative follow-up of patients revealed that 87.5% (21/24) of patients had died and three cases were not able to be tracked. In all cases, the mean survival time was 12.1 mo. While 100% of the HAS samples were positive for ERG expression, expression of the other markers was more variable. CD31 was expressed in 79.2% (19/24) of samples, CD34 was expressed in 87.5% (21/24) of samples and FVIIIRAg was expressed in 41.7% (10/24) of samples.ERG is a more sensitive and specific diagnostic marker for hepatic angiosarcoma in comparison to CD31, CD34 and FVIIIRAg." @default.
• W2070733023 created "2016-06-24" @default.
• W2070733023 creator A5010401056 @default.
• W2070733023 creator A5031753073 @default.
• W2070733023 creator A5045689867 @default.
• W2070733023 creator A5070167890 @default.
• W2070733023 date "2014-01-01" @default.
• W2070733023 modified "2023-10-15" @default.
• W2070733023 title "Transcription factor ERG is a specific and sensitive diagnostic marker for hepatic angiosarcoma" @default.
• W2070733023 cites W1498841221 @default.
• W2070733023 cites W1544776157 @default.
• W2070733023 cites W1575345943 @default.
• W2070733023 cites W1935828301 @default.
• W2070733023 cites W1976978794 @default.
• W2070733023 cites W1979809572 @default.
• W2070733023 cites W1980213927 @default.
• W2070733023 cites W1991585166 @default.
• W2070733023 cites W2005345468 @default.
• W2070733023 cites W2010644808 @default.
• W2070733023 cites W2013292886 @default.
• W2070733023 cites W2029970671 @default.
• W2070733023 cites W2050811882 @default.
• W2070733023 cites W2053017372 @default.
• W2070733023 cites W2070752369 @default.
• W2070733023 cites W2071323844 @default.
• W2070733023 cites W2080853888 @default.
• W2070733023 cites W2089145440 @default.
• W2070733023 cites W2095174227 @default.
• W2070733023 cites W2099436620 @default.
• W2070733023 cites W2102025300 @default.
• W2070733023 cites W2125340759 @default.
• W2070733023 cites W2137565444 @default.
• W2070733023 cites W2152381741 @default.
• W2070733023 cites W2156137898 @default.
• W2070733023 cites W2158288129 @default.
• W2070733023 cites W2160790595 @default.
• W2070733023 cites W2290519607 @default.
• W2070733023 cites W2419125848 @default.
• W2070733023 cites W2466318884 @default.
• W2070733023 cites W33617873 @default.
• W2070733023 doi "https://doi.org/10.3748/wjg.v20.i13.3672" @default.
• W2070733023 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3974537" @default.
• W2070733023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24707153" @default.
• W2070733023 hasPublicationYear "2014" @default.
• W2070733023 type Work @default.
• W2070733023 sameAs 2070733023 @default.
• W2070733023 citedByCount "37" @default.
• W2070733023 countsByYear W20707330232014 @default.
• W2070733023 countsByYear W20707330232015 @default.
• W2070733023 countsByYear W20707330232016 @default.
• W2070733023 countsByYear W20707330232017 @default.
• W2070733023 countsByYear W20707330232018 @default.
• W2070733023 countsByYear W20707330232019 @default.
• W2070733023 countsByYear W20707330232020 @default.
• W2070733023 countsByYear W20707330232021 @default.
• W2070733023 countsByYear W20707330232022 @default.
• W2070733023 countsByYear W20707330232023 @default.
• W2070733023 crossrefType "journal-article" @default.
• W2070733023 hasAuthorship W2070733023A5010401056 @default.
• W2070733023 hasAuthorship W2070733023A5031753073 @default.
• W2070733023 hasAuthorship W2070733023A5045689867 @default.
• W2070733023 hasAuthorship W2070733023A5070167890 @default.
• W2070733023 hasBestOaLocation W20707330231 @default.
• W2070733023 hasConcept C10205521 @default.
• W2070733023 hasConcept C125473707 @default.
• W2070733023 hasConcept C126322002 @default.
• W2070733023 hasConcept C142724271 @default.
• W2070733023 hasConcept C204232928 @default.
• W2070733023 hasConcept C2778939058 @default.
• W2070733023 hasConcept C2779217266 @default.
• W2070733023 hasConcept C28328180 @default.
• W2070733023 hasConcept C54355233 @default.
• W2070733023 hasConcept C71924100 @default.
• W2070733023 hasConcept C86803240 @default.
• W2070733023 hasConceptScore W2070733023C10205521 @default.
• W2070733023 hasConceptScore W2070733023C125473707 @default.
• W2070733023 hasConceptScore W2070733023C126322002 @default.
• W2070733023 hasConceptScore W2070733023C142724271 @default.
• W2070733023 hasConceptScore W2070733023C204232928 @default.
• W2070733023 hasConceptScore W2070733023C2778939058 @default.
• W2070733023 hasConceptScore W2070733023C2779217266 @default.
• W2070733023 hasConceptScore W2070733023C28328180 @default.
• W2070733023 hasConceptScore W2070733023C54355233 @default.
• W2070733023 hasConceptScore W2070733023C71924100 @default.
• W2070733023 hasConceptScore W2070733023C86803240 @default.
• W2070733023 hasIssue "13" @default.
• W2070733023 hasLocation W20707330231 @default.
• W2070733023 hasLocation W20707330232 @default.
• W2070733023 hasLocation W20707330233 @default.
• W2070733023 hasLocation W20707330234 @default.
• W2070733023 hasOpenAccess W2070733023 @default.
• W2070733023 hasPrimaryLocation W20707330231 @default.
• W2070733023 hasRelatedWork W1994580667 @default.
• W2070733023 hasRelatedWork W2037379733 @default.
• W2070733023 hasRelatedWork W2188469443 @default.
• W2070733023 hasRelatedWork W2189142675 @default.
• W2070733023 hasRelatedWork W2391679506 @default.
• W2070733023 hasRelatedWork W2412130470 @default.

• next