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- W2070740144 endingPage "33" @default.
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- W2070740144 abstract "Cholinergic neurons and nicotinic acetylcholine receptors (nAChRs) in the brain participate in diverse functions: reward, learning and memory, mood, sensory processing, pain, and neuroprotection. Nicotinic systems also have well-known roles in drug abuse. Here, we review recent insights into nicotinic function, linking exogenous and endogenous manipulations of nAChRs to alterations in synapses, circuits, and behavior. We also discuss how these contemporary advances can motivate attempts to exploit nicotinic systems therapeutically in Parkinson's disease, cognitive decline, epilepsy, and schizophrenia. Cholinergic neurons and nicotinic acetylcholine receptors (nAChRs) in the brain participate in diverse functions: reward, learning and memory, mood, sensory processing, pain, and neuroprotection. Nicotinic systems also have well-known roles in drug abuse. Here, we review recent insights into nicotinic function, linking exogenous and endogenous manipulations of nAChRs to alterations in synapses, circuits, and behavior. We also discuss how these contemporary advances can motivate attempts to exploit nicotinic systems therapeutically in Parkinson's disease, cognitive decline, epilepsy, and schizophrenia." @default.
- W2070740144 created "2016-06-24" @default.
- W2070740144 creator A5024286952 @default.
- W2070740144 creator A5069369115 @default.
- W2070740144 creator A5075514675 @default.
- W2070740144 date "2011-04-01" @default.
- W2070740144 modified "2023-09-30" @default.
- W2070740144 title "Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses" @default.
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