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- W2070740555 abstract "Five experiments examined the reinstatement of fear (freezing) produced by recent reexposure to a dangerous context. Rats were trained to fear a conditioned stimulus (CS) and a distinctive context with shock. The CS was then extinguished. A 2-min interval between reexposure to the dangerous context and presentation of the extinguished CS in a different context reinstated freezing when the CS was tested the next day. Propranolol (a beta-adrenergic antagonist) blocked reinstatement of extinguished fear without decreasing freezing to a nonextinguished CS. Administration of epinephrine (an adrenergic agonist) reinstated extinguished fear without reexposure to the dangerous context. The results suggest a role for beta-adrenergic activity elicited by exposure to a conditioned context in the reinstatement of extinguished fear." @default.
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- W2070740555 date "2005-01-01" @default.
- W2070740555 modified "2023-10-04" @default.
- W2070740555 title "Reinstatement of extinguished fear by β-adrenergic arousal elicited by a conditioned context." @default.
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- W2070740555 doi "https://doi.org/10.1037/0735-7044.119.6.1662" @default.
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