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- W2070778834 abstract "We report a case where hepatitis was the only manifestation of acute brucellosis.A 33-year-old female patient was admit-ted to our clinic with complaints of fever, chills, headache, nausea and dark urine. Her temperature was 38.4°C, pulse was 76/min, respiratory rate was 16/min and blood pressure was 110/80 mmHg. Physi-cal examination revealed yellow sclera and a hepatosplenomegaly of 1 cm. The labora-tory test results revealed a leukocyte count of 3.8x109/L, C-reactive protein (CRP) of 26 mg/L, and an erythrocyte sedimenta-tion rate (ESR) of 17 mm/h. Serum alanine transferase (ALT) level was 372 U/L, se-rum aspartate transferase (AST) 303 U/L, serum alkaline phosphatase 454 U/L, se-rum γ-glutamyl transpeptidase 192 U/L and total bilirubin concentration was 3.2 mg/dL. The HBs-Ag, anti-HBc IgM, anti-HAV IgM, anti-HCV, anti-CMV IgM, anti-VCA IgM and Gruber Widal tests were negative. The patient had a positive history of fresh cheese ingestion, so a Wright agglutination test was also performed and the titer was found to be positive at 1/320. Abdominal ultrasonography showed moderate hepat-osplenomegaly, without any structural or morphological changes. With these findings, she was diagnosed as having acute hepatitis due to brucellosis. Blood cultures had been performed before the antibiotic therapy was started. Doxycycline 200 mg/d and strepto-mycin 1 g/d treatment were started. The fe-ver subsided on the fourth day of the treat-ment and blood cultures isolated" @default.
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- W2070778834 date "2010-11-01" @default.
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- W2070778834 title "An unusual presentation of brucellosis: acute hepatitis" @default.
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- W2070778834 doi "https://doi.org/10.1016/s1413-8670(10)70127-6" @default.
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