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- W2070822016 abstract "The potential of comparative studies on histones for use in protistan evolution is discussed, using algal histones as specific examples. A basic premise for the importance of histones in protistan evolution is the observation that these proteins are completely absent in prokaryotes (and cytoplasmic organelles), but with few exceptions, the same five major histone types are found in all higher plants and animals. Since the histone content of the algae and other protists is not constant, some of these organisms may represent transition forms between the prokaryotic and eukaryotic modes of packaging the genetic material. Comparative studies of protistan histones may thus be of help in determining evolutionary relationships. However, several problems are encountered with protistan histones, including difficulties in isolating nuclei, proteolytic degradation, anomalous gel migration of histones, and difficulties in histone identification. Because of the above problems, and the observed variability in protistan histones, it is suggested that several criteria be employed for histone identification in protists." @default.
- W2070822016 created "2016-06-24" @default.
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- W2070822016 date "1985-01-01" @default.
- W2070822016 modified "2023-10-18" @default.
- W2070822016 title "Histones in protistan evolution" @default.
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- W2070822016 doi "https://doi.org/10.1016/0303-2647(85)90025-5" @default.
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