FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070853821> ?p ?o ?g. }

• W2070853821 endingPage "190" @default.
• W2070853821 startingPage "181" @default.
• W2070853821 abstract "The functional attributes of specific point mutations, R30K, S291G, and I392T, associated with full-length acetylcholinesterase (AChE) cDNAs of organophosphate (OP)- and carbamate-resistant Colorado potato beetles (CPB), were determined using site-directed mutagenesis and baculovirus expression. Enzymatic and inhibitory properties of altered recombinant acetylcholinesterases (rAChEs) were examined. S291G increased the hydrolysis of substrates with larger substituted alkyl groups (e.g., BTC vs ATC) and increased the inhibitory action of inhibitors with larger alkyl groups (e.g., paraoxon, DFP, and N-propyl carbofuran vs. azinphosmethyl-oxon and N-methyl carbofuran). R30K in conjunction with S291G enhanced the hydrolysis activity of larger substrates and the inhibitory action of larger inhibitors. I392T attenuated the effects of S291G in that the altered rAChE with both S291G and I392T elicited substrate specificity and inhibitory properties more similar to the susceptible form of AChE without mutations." @default.
• W2070853821 created "2016-06-24" @default.
• W2070853821 creator A5052361629 @default.
• W2070853821 creator A5068694806 @default.
• W2070853821 creator A5081161757 @default.
• W2070853821 date "2007-06-01" @default.
• W2070853821 modified "2023-10-17" @default.
• W2070853821 title "Functional analysis of mutations in expressed acetylcholinesterase that result in azinphosmethyl and carbofuran resistance in Colorado potato beetle" @default.
• W2070853821 cites W1968275714 @default.
• W2070853821 cites W1971048984 @default.
• W2070853821 cites W1991650762 @default.
• W2070853821 cites W1994283397 @default.
• W2070853821 cites W2001803866 @default.
• W2070853821 cites W2011000826 @default.
• W2070853821 cites W2013644867 @default.
• W2070853821 cites W2021239536 @default.
• W2070853821 cites W2034300645 @default.
• W2070853821 cites W2036330601 @default.
• W2070853821 cites W2038215339 @default.
• W2070853821 cites W2055307314 @default.
• W2070853821 cites W2055818529 @default.
• W2070853821 cites W2057294413 @default.
• W2070853821 cites W2060387458 @default.
• W2070853821 cites W2074874926 @default.
• W2070853821 cites W2093925770 @default.
• W2070853821 cites W2109157221 @default.
• W2070853821 cites W2158533759 @default.
• W2070853821 cites W2331972368 @default.
• W2070853821 cites W2335644013 @default.
• W2070853821 doi "https://doi.org/10.1016/j.pestbp.2006.11.004" @default.
• W2070853821 hasPublicationYear "2007" @default.
• W2070853821 type Work @default.
• W2070853821 sameAs 2070853821 @default.
• W2070853821 citedByCount "27" @default.
• W2070853821 countsByYear W20708538212012 @default.
• W2070853821 countsByYear W20708538212013 @default.
• W2070853821 countsByYear W20708538212014 @default.
• W2070853821 countsByYear W20708538212015 @default.
• W2070853821 countsByYear W20708538212016 @default.
• W2070853821 countsByYear W20708538212017 @default.
• W2070853821 countsByYear W20708538212019 @default.
• W2070853821 countsByYear W20708538212021 @default.
• W2070853821 countsByYear W20708538212022 @default.
• W2070853821 countsByYear W20708538212023 @default.
• W2070853821 crossrefType "journal-article" @default.
• W2070853821 hasAuthorship W2070853821A5052361629 @default.
• W2070853821 hasAuthorship W2070853821A5068694806 @default.
• W2070853821 hasAuthorship W2070853821A5081161757 @default.
• W2070853821 hasConcept C134018914 @default.
• W2070853821 hasConcept C161176658 @default.
• W2070853821 hasConcept C17077164 @default.
• W2070853821 hasConcept C181199279 @default.
• W2070853821 hasConcept C185592680 @default.
• W2070853821 hasConcept C2776588719 @default.
• W2070853821 hasConcept C2777207434 @default.
• W2070853821 hasConcept C2778359560 @default.
• W2070853821 hasConcept C2778816929 @default.
• W2070853821 hasConcept C2779059548 @default.
• W2070853821 hasConcept C2779303437 @default.
• W2070853821 hasConcept C2780862241 @default.
• W2070853821 hasConcept C55493867 @default.
• W2070853821 hasConcept C6557445 @default.
• W2070853821 hasConcept C71240020 @default.
• W2070853821 hasConcept C86803240 @default.
• W2070853821 hasConcept C98274493 @default.
• W2070853821 hasConceptScore W2070853821C134018914 @default.
• W2070853821 hasConceptScore W2070853821C161176658 @default.
• W2070853821 hasConceptScore W2070853821C17077164 @default.
• W2070853821 hasConceptScore W2070853821C181199279 @default.
• W2070853821 hasConceptScore W2070853821C185592680 @default.
• W2070853821 hasConceptScore W2070853821C2776588719 @default.
• W2070853821 hasConceptScore W2070853821C2777207434 @default.
• W2070853821 hasConceptScore W2070853821C2778359560 @default.
• W2070853821 hasConceptScore W2070853821C2778816929 @default.
• W2070853821 hasConceptScore W2070853821C2779059548 @default.
• W2070853821 hasConceptScore W2070853821C2779303437 @default.
• W2070853821 hasConceptScore W2070853821C2780862241 @default.
• W2070853821 hasConceptScore W2070853821C55493867 @default.
• W2070853821 hasConceptScore W2070853821C6557445 @default.
• W2070853821 hasConceptScore W2070853821C71240020 @default.
• W2070853821 hasConceptScore W2070853821C86803240 @default.
• W2070853821 hasConceptScore W2070853821C98274493 @default.
• W2070853821 hasIssue "2" @default.
• W2070853821 hasLocation W20708538211 @default.
• W2070853821 hasOpenAccess W2070853821 @default.
• W2070853821 hasPrimaryLocation W20708538211 @default.
• W2070853821 hasRelatedWork W1974384232 @default.
• W2070853821 hasRelatedWork W2006029626 @default.
• W2070853821 hasRelatedWork W2060845671 @default.
• W2070853821 hasRelatedWork W2077942428 @default.
• W2070853821 hasRelatedWork W2395149724 @default.
• W2070853821 hasRelatedWork W2415165030 @default.
• W2070853821 hasRelatedWork W2419777824 @default.
• W2070853821 hasRelatedWork W3021391997 @default.
• W2070853821 hasRelatedWork W2273714756 @default.
• W2070853821 hasRelatedWork W2291130226 @default.
• W2070853821 hasVolume "88" @default.
• W2070853821 isParatext "false" @default.

• next