Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070859585> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2070859585 endingPage "1819" @default.
- W2070859585 startingPage "1816" @default.
- W2070859585 abstract "The aim of this prospective trial was to compare the effect of different long-acting insulin preparations injected at bedtime on glucose concentrations in patients with type 2 diabetes omitting breakfast and lunch the next day.Twenty patients (ten women) with type 2 diabetes who were on an intensified insulin therapy participated. Mean (+/-SD) age was 63 +/- 10 years, diabetes duration 18 +/- 9 years, BMI 32.5 +/- 5 kg/m(2), and HbA(1c) 7.3 +/- 0.7%. Patients received neutral protamine Hagedorn (NPH) insulin, insulin detemir or insulin glargine for at least 2 months; doses were adjusted to achieve morning blood glucose levels of <7 mmol/l. At the end of the respective treatment period, the long-acting insulin was injected at bedtime (at 22:45 hours) as usual but patients refrained from breakfast and lunch the next day; glucose was measured by a continuous glucose monitoring system (CGMS).Comparable glucose target ranges were reached at midnight (5.8 to 6.1 mmol/l) and at 07:00 hours (6.7 to 6.9 mmol/l) with all three insulin preparations, using mean doses of 29 +/- 10 U (NPH insulin), 33 +/- 13 U (insulin detemir), and 32 +/- 12 U (insulin glargine). Glucose levels between midnight and 07:00 hours were not significantly different for the three insulin preparations. Symptomatic hypoglycaemia did not occur from 08:00 to 16:00 hours; glucose concentrations during this time were slightly lower with NPH insulin than with insulin detemir (p = 0.012) and insulin glargine (p = 0.049).Following bedtime injection of NPH insulin or of the analogues insulin detemir or insulin glargine, fasting glucose <7 mmol/l was achieved in the morning, without subsequent hypoglycaemia when participants continued to fast during the day." @default.
- W2070859585 created "2016-06-24" @default.
- W2070859585 creator A5007837138 @default.
- W2070859585 creator A5020046662 @default.
- W2070859585 creator A5041905133 @default.
- W2070859585 creator A5047142547 @default.
- W2070859585 creator A5051239331 @default.
- W2070859585 date "2009-06-30" @default.
- W2070859585 modified "2023-09-27" @default.
- W2070859585 title "Omitting breakfast and lunch after injection of different long-acting insulin preparations at bedtime: a prospective study in patients with type 2 diabetes" @default.
- W2070859585 cites W1550111394 @default.
- W2070859585 cites W1964547390 @default.
- W2070859585 cites W1978936196 @default.
- W2070859585 cites W1997915932 @default.
- W2070859585 cites W2000247073 @default.
- W2070859585 cites W2005932743 @default.
- W2070859585 cites W2058777107 @default.
- W2070859585 cites W2130931445 @default.
- W2070859585 cites W2136164787 @default.
- W2070859585 cites W2158144637 @default.
- W2070859585 doi "https://doi.org/10.1007/s00125-009-1439-z" @default.
- W2070859585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19565212" @default.
- W2070859585 hasPublicationYear "2009" @default.
- W2070859585 type Work @default.
- W2070859585 sameAs 2070859585 @default.
- W2070859585 citedByCount "5" @default.
- W2070859585 crossrefType "journal-article" @default.
- W2070859585 hasAuthorship W2070859585A5007837138 @default.
- W2070859585 hasAuthorship W2070859585A5020046662 @default.
- W2070859585 hasAuthorship W2070859585A5041905133 @default.
- W2070859585 hasAuthorship W2070859585A5047142547 @default.
- W2070859585 hasAuthorship W2070859585A5051239331 @default.
- W2070859585 hasBestOaLocation W20708595851 @default.
- W2070859585 hasConcept C126322002 @default.
- W2070859585 hasConcept C134018914 @default.
- W2070859585 hasConcept C19720800 @default.
- W2070859585 hasConcept C2777180221 @default.
- W2070859585 hasConcept C2778537899 @default.
- W2070859585 hasConcept C2778804033 @default.
- W2070859585 hasConcept C2779306644 @default.
- W2070859585 hasConcept C2779920387 @default.
- W2070859585 hasConcept C2780668416 @default.
- W2070859585 hasConcept C2780677441 @default.
- W2070859585 hasConcept C2781232474 @default.
- W2070859585 hasConcept C555293320 @default.
- W2070859585 hasConcept C71924100 @default.
- W2070859585 hasConceptScore W2070859585C126322002 @default.
- W2070859585 hasConceptScore W2070859585C134018914 @default.
- W2070859585 hasConceptScore W2070859585C19720800 @default.
- W2070859585 hasConceptScore W2070859585C2777180221 @default.
- W2070859585 hasConceptScore W2070859585C2778537899 @default.
- W2070859585 hasConceptScore W2070859585C2778804033 @default.
- W2070859585 hasConceptScore W2070859585C2779306644 @default.
- W2070859585 hasConceptScore W2070859585C2779920387 @default.
- W2070859585 hasConceptScore W2070859585C2780668416 @default.
- W2070859585 hasConceptScore W2070859585C2780677441 @default.
- W2070859585 hasConceptScore W2070859585C2781232474 @default.
- W2070859585 hasConceptScore W2070859585C555293320 @default.
- W2070859585 hasConceptScore W2070859585C71924100 @default.
- W2070859585 hasIssue "9" @default.
- W2070859585 hasLocation W20708595851 @default.
- W2070859585 hasLocation W20708595852 @default.
- W2070859585 hasOpenAccess W2070859585 @default.
- W2070859585 hasPrimaryLocation W20708595851 @default.
- W2070859585 hasRelatedWork W1971493468 @default.
- W2070859585 hasRelatedWork W2003744723 @default.
- W2070859585 hasRelatedWork W2035488573 @default.
- W2070859585 hasRelatedWork W2077148563 @default.
- W2070859585 hasRelatedWork W2091307485 @default.
- W2070859585 hasRelatedWork W2102602264 @default.
- W2070859585 hasRelatedWork W2183379638 @default.
- W2070859585 hasRelatedWork W2324957922 @default.
- W2070859585 hasRelatedWork W3133553555 @default.
- W2070859585 hasRelatedWork W1977286315 @default.
- W2070859585 hasVolume "52" @default.
- W2070859585 isParatext "false" @default.
- W2070859585 isRetracted "false" @default.
- W2070859585 magId "2070859585" @default.
- W2070859585 workType "article" @default.