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- W2070880984 abstract "Purpose of review Cardiovascular disease accounts for the majority of morbidity and mortality in patients with chronic kidney disease (CKD). This review therefore concentrates on CKD from the viewpoint of the cardiologist. Recent findings Studies have identified several explanations for this observation, including high rates of risk factors for cardiovascular disease, lesser use of cardioprotective strategies, adverse outcomes with cardiovascular drugs and procedures, and accelerated atherosclerosis and myocardial disease in CKD. Because recent studies have rigorously controlled for confounding factors, there is an emerging recognition that CKD is an independent cardiovascular risk state. Conversely, CKD appears to be the result of systemic atherosclerosis. The relative under-utilization of cardioprotective therapies has been an increasingly reported finding in the literature. It appears that conventional cardiovascular risk factor reduction in both the chronic and acute care settings has a greater relative benefit in those patients with CKD than in those with normal renal function. Summary CKD is an independent cardiovascular risk state. Hence, there is a strong rationale for research in CKD patients into the pathogenesis of CVD. In addition, there are multiple opportunities for improving cardiovascular outcomes in patients with CKD, including both chronic and acute cardiovascular risk reduction." @default.
- W2070880984 created "2016-06-24" @default.
- W2070880984 creator A5008382551 @default.
- W2070880984 date "2004-11-01" @default.
- W2070880984 modified "2023-10-12" @default.
- W2070880984 title "Cardiovascular disease in chronic kidney disease from a cardiologistʼs perspective" @default.
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- W2070880984 doi "https://doi.org/10.1097/00041552-200411000-00003" @default.
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