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• W2070917861 abstract "Carcinoid tumors are neuroendocrine malignancies that originate in the neuroectodermal cells of the Amine, Peptide Uptake and Decarboxylation system dispersed in the gastrointestinal mucosa and representing about 80–88% of tumors of cecal appendix. These are tumors usually diagnosed at appendectomies, and it is estimated that from each 100 appendectomies yearly performed, at least one case is a neuroendocrine tumor. To report the experience of an University Teaching Hospital in health and reference at the east side of São Paulo and great São Paulo in cases of these rare appendicular tumors, with emphasis on the importance of these descriptions, as probably are rare those surgeons in particular who will acquire extensive wisdom in these cases. Retrospective analysis of 237 patients who underwent appendectomy from September 2010 to September 2012 in the Hospital Santa Marcelina-SP. We evaluated data on age, gender, initial clinical presentation and surgical findings of patients undergoing appendectomy with subsequent anatomic and immunopathological diagnosis of carcinoid tumor of cecal appendix. The presence of a carcinoid tumor of the appendix was observed in 5 patients, which corresponds to 2.1% of all appendectomies performed. Regarding gender, 4 patients (80%) were female and the average age was 34.2 years, with a range from 17 to 68 years. In all patients the initial hypothesis for surgery indication was acute appendicitis, with an intraoperative finding of necroperforated phase acute appendicitis in 3 patients (60%). The therapeutical conduct after the diagnosis of carcinoid tumors of the appendix must be based on the data provided by pathological and immunohistochemical studies, besides the judicious judgment of the attending physician. Os tumores carcinoides são neoplasias malignas neuroendócrinas que se originam em células neuroectodérmicas do sistema APUD (Amine, Peptide Uptake and Decarboxylation), dispersas na mucosa gastrointestinal e que representam cerca de 80-88% das neoplasias do apêndice cecal. São tumores diagnosticados geralmente durante apendicectomias e estima-se que de cada 100 apendicectomias realizadas por ano, ao menos um caso será TNE. Objetiva-se nesse artigo relatar experiência de Hospital Universitário e de Ensino (HUE) em saúde e referência na zona leste de São Paulo e grande São Paulo em casos desses raros tumores apendiculares, com ênfase na importância dessas descrições, já que provavelmente raros cirurgiões em particular irão adquirir uma extensa sapiência nesses casos. Análise retrospectiva de 237 pacientes submetidos à apendicectomia no período de setembro de 2010 a setembro de 2012 no Hospital Santa Marcelina-SP. Foram avaliados os dados referentes a idade, sexo, quadro clínico inicial, achados operatórios dos pacientes submetidos à apendicectomia com posterior diagnóstico anatomopatológico e imunopatológico de tumor carcinoide de apêndice. Verificou-se a presença de tumor carcinoide de apêndice em 5 pacientes, o que corresponde a 2,1% das apendicectomias realizadas. Com relação ao gênero, 4 pacientes (80%) eram mulheres e a média de idade foi de 34,2 anos, com variação de 17 a 68 anos. Em todos os pacientes a hipótese inicial para indicação de cirurgia fora de apendicite aguda, com achado intra-operatório de apendicite aguda em fase necroperfurada em 3 pacientes (60%). A conduta após o diagnóstico de tumores carcinoides de apêndice cecal deve ser alicerçada nos dados fornecidos por exames anatomopatológicos e imunoistoquímicos, além do julgamento criterioso do médico assistente." @default.
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• W2070917861 date "2014-10-01" @default.
• W2070917861 modified "2023-09-23" @default.
• W2070917861 title "Carcinoid tumor of cecal appendix: one-year incidence at the Santa Marcelina Hospital" @default.
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• W2070917861 doi "https://doi.org/10.1016/j.jcol.2014.08.009" @default.
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