FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070920444> ?p ?o ?g. }

• W2070920444 endingPage "40" @default.
• W2070920444 startingPage "37" @default.
• W2070920444 abstract "Mutations in PTEN-induced putative kinase 1 (PINK1) cause recessive forms of Parkinson's disease (PD). PINK1 acts upstream of parkin, regulating mitochondrial elimination (mitophagy) in cultured cells treated with mitochondrial uncouplers that cause mitochondrial depolarization. PINK1 loss-of-function decreases mitochondrial membrane potential, resulting in mitochondrial dysfunction, although the exact function of PINK1 in mitochondria has not been fully elucidated. We have previously found that PINK1 deficiency causes a decrease in mitochondrial membrane potential, which is not due to a proton leak, but to respiratory chain defects. Here, we examine mitochondrial respiratory chain defects in PINK1-deficient cells, and find both complex I and complex III are defective. These results suggest that mitochondrial respiratory chain defects may be associated with PD pathogenesis caused by mutations in the PINK1 gene." @default.
• W2070920444 created "2016-06-24" @default.
• W2070920444 creator A5006189922 @default.
• W2070920444 creator A5009187834 @default.
• W2070920444 creator A5014705038 @default.
• W2070920444 creator A5017935399 @default.
• W2070920444 creator A5039592216 @default.
• W2070920444 date "2014-09-01" @default.
• W2070920444 modified "2023-09-27" @default.
• W2070920444 title "Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1" @default.
• W2070920444 cites W1515247384 @default.
• W2070920444 cites W1541799695 @default.
• W2070920444 cites W1965285497 @default.
• W2070920444 cites W1969800514 @default.
• W2070920444 cites W1983066584 @default.
• W2070920444 cites W1990287702 @default.
• W2070920444 cites W2009503896 @default.
• W2070920444 cites W2024991268 @default.
• W2070920444 cites W2025130486 @default.
• W2070920444 cites W2028339345 @default.
• W2070920444 cites W2029009175 @default.
• W2070920444 cites W2032546372 @default.
• W2070920444 cites W2038878427 @default.
• W2070920444 cites W2050849483 @default.
• W2070920444 cites W2050865611 @default.
• W2070920444 cites W2055538245 @default.
• W2070920444 cites W2067635405 @default.
• W2070920444 cites W2068119233 @default.
• W2070920444 cites W2085133992 @default.
• W2070920444 cites W2087957743 @default.
• W2070920444 cites W2092871687 @default.
• W2070920444 cites W2109326232 @default.
• W2070920444 cites W2111682630 @default.
• W2070920444 cites W2132417146 @default.
• W2070920444 cites W2135335338 @default.
• W2070920444 cites W2136388422 @default.
• W2070920444 cites W2138311396 @default.
• W2070920444 cites W2143161560 @default.
• W2070920444 cites W2155015733 @default.
• W2070920444 cites W2171752318 @default.
• W2070920444 doi "https://doi.org/10.1016/j.neulet.2014.07.045" @default.
• W2070920444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25092611" @default.
• W2070920444 hasPublicationYear "2014" @default.
• W2070920444 type Work @default.
• W2070920444 sameAs 2070920444 @default.
• W2070920444 citedByCount "30" @default.
• W2070920444 countsByYear W20709204442014 @default.
• W2070920444 countsByYear W20709204442015 @default.
• W2070920444 countsByYear W20709204442016 @default.
• W2070920444 countsByYear W20709204442017 @default.
• W2070920444 countsByYear W20709204442018 @default.
• W2070920444 countsByYear W20709204442019 @default.
• W2070920444 countsByYear W20709204442020 @default.
• W2070920444 countsByYear W20709204442021 @default.
• W2070920444 countsByYear W20709204442022 @default.
• W2070920444 countsByYear W20709204442023 @default.
• W2070920444 crossrefType "journal-article" @default.
• W2070920444 hasAuthorship W2070920444A5006189922 @default.
• W2070920444 hasAuthorship W2070920444A5009187834 @default.
• W2070920444 hasAuthorship W2070920444A5014705038 @default.
• W2070920444 hasAuthorship W2070920444A5017935399 @default.
• W2070920444 hasAuthorship W2070920444A5039592216 @default.
• W2070920444 hasConcept C104317684 @default.
• W2070920444 hasConcept C126322002 @default.
• W2070920444 hasConcept C190283241 @default.
• W2070920444 hasConcept C203522944 @default.
• W2070920444 hasConcept C24586158 @default.
• W2070920444 hasConcept C2776804853 @default.
• W2070920444 hasConcept C2777614518 @default.
• W2070920444 hasConcept C2777668072 @default.
• W2070920444 hasConcept C2779134260 @default.
• W2070920444 hasConcept C2779324830 @default.
• W2070920444 hasConcept C2779734285 @default.
• W2070920444 hasConcept C28859421 @default.
• W2070920444 hasConcept C3020377403 @default.
• W2070920444 hasConcept C3020761558 @default.
• W2070920444 hasConcept C54355233 @default.
• W2070920444 hasConcept C71924100 @default.
• W2070920444 hasConcept C86803240 @default.
• W2070920444 hasConcept C95444343 @default.
• W2070920444 hasConceptScore W2070920444C104317684 @default.
• W2070920444 hasConceptScore W2070920444C126322002 @default.
• W2070920444 hasConceptScore W2070920444C190283241 @default.
• W2070920444 hasConceptScore W2070920444C203522944 @default.
• W2070920444 hasConceptScore W2070920444C24586158 @default.
• W2070920444 hasConceptScore W2070920444C2776804853 @default.
• W2070920444 hasConceptScore W2070920444C2777614518 @default.
• W2070920444 hasConceptScore W2070920444C2777668072 @default.
• W2070920444 hasConceptScore W2070920444C2779134260 @default.
• W2070920444 hasConceptScore W2070920444C2779324830 @default.
• W2070920444 hasConceptScore W2070920444C2779734285 @default.
• W2070920444 hasConceptScore W2070920444C28859421 @default.
• W2070920444 hasConceptScore W2070920444C3020377403 @default.
• W2070920444 hasConceptScore W2070920444C3020761558 @default.
• W2070920444 hasConceptScore W2070920444C54355233 @default.
• W2070920444 hasConceptScore W2070920444C71924100 @default.
• W2070920444 hasConceptScore W2070920444C86803240 @default.
• W2070920444 hasConceptScore W2070920444C95444343 @default.

• next