FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070959227> ?p ?o ?g. }

• W2070959227 endingPage "896" @default.
• W2070959227 startingPage "889" @default.
• W2070959227 abstract "In two murine models we studied Trypanosoma cruzi reinfection in the acute and chronic phase of experimental Chagas' disease in order to elucidate the relevance of reinfections in determining the variability of cardiac symptoms and the irreversible cardiac damage. They were followed for 120 and 600 days post infection (p.i.) for the acute and chronic model, respectively. Reinfected mice reached higher parasitaemia levels than infected mice. The survival was 33 and 21% in the chronic phase for mice reinfected in the acute phase and 13% for mice reinfected in the chronic stage at the end of the experiments. Sixty-six percent of the infected group presented electrocardiographic abnormalities (heart frequency, prolonged PQ segment or QRS complex) in the chronic stage whereas 100% of the reinfected animals exhibited electric cardiac dysfunction since 90 and 390 days p.i. for the acute and chronic reinfected model, respectively (P<0.01). Heart histopathological studies showed fibrosis and necrosis areas and mononuclear infiltrates supporting the view that parasite persistence is a major factor in continuing the tissue inflammation. This work shows that T. cruzi reinfections could be related to the variability and severity of the clinical course of Chagas' disease and that parasite persistence is involved in exacerbation of the disease." @default.
• W2070959227 created "2016-06-24" @default.
• W2070959227 creator A5023992420 @default.
• W2070959227 creator A5028510311 @default.
• W2070959227 creator A5034693654 @default.
• W2070959227 creator A5049106380 @default.
• W2070959227 creator A5062285317 @default.
• W2070959227 creator A5078908471 @default.
• W2070959227 creator A5062832612 @default.
• W2070959227 date "2002-06-01" @default.
• W2070959227 modified "2023-10-01" @default.
• W2070959227 title "Trypanosoma cruzi reinfections in mice determine the severity of cardiac damage" @default.
• W2070959227 cites W1599893553 @default.
• W2070959227 cites W1768923368 @default.
• W2070959227 cites W1979245971 @default.
• W2070959227 cites W1987653890 @default.
• W2070959227 cites W1996541164 @default.
• W2070959227 cites W2012195873 @default.
• W2070959227 cites W2013930187 @default.
• W2070959227 cites W2023871287 @default.
• W2070959227 cites W2038369799 @default.
• W2070959227 cites W2048589505 @default.
• W2070959227 cites W2091431690 @default.
• W2070959227 cites W2093070289 @default.
• W2070959227 cites W2096133233 @default.
• W2070959227 cites W2108818445 @default.
• W2070959227 cites W2150468905 @default.
• W2070959227 cites W2171131376 @default.
• W2070959227 cites W2306320281 @default.
• W2070959227 cites W2405619083 @default.
• W2070959227 cites W35514906 @default.
• W2070959227 cites W4211027594 @default.
• W2070959227 doi "https://doi.org/10.1016/s0020-7519(02)00023-1" @default.
• W2070959227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12062560" @default.
• W2070959227 hasPublicationYear "2002" @default.
• W2070959227 type Work @default.
• W2070959227 sameAs 2070959227 @default.
• W2070959227 citedByCount "65" @default.
• W2070959227 countsByYear W20709592272012 @default.
• W2070959227 countsByYear W20709592272013 @default.
• W2070959227 countsByYear W20709592272014 @default.
• W2070959227 countsByYear W20709592272015 @default.
• W2070959227 countsByYear W20709592272016 @default.
• W2070959227 countsByYear W20709592272017 @default.
• W2070959227 countsByYear W20709592272018 @default.
• W2070959227 countsByYear W20709592272019 @default.
• W2070959227 countsByYear W20709592272020 @default.
• W2070959227 countsByYear W20709592272021 @default.
• W2070959227 countsByYear W20709592272022 @default.
• W2070959227 countsByYear W20709592272023 @default.
• W2070959227 crossrefType "journal-article" @default.
• W2070959227 hasAuthorship W2070959227A5023992420 @default.
• W2070959227 hasAuthorship W2070959227A5028510311 @default.
• W2070959227 hasAuthorship W2070959227A5034693654 @default.
• W2070959227 hasAuthorship W2070959227A5049106380 @default.
• W2070959227 hasAuthorship W2070959227A5062285317 @default.
• W2070959227 hasAuthorship W2070959227A5062832612 @default.
• W2070959227 hasAuthorship W2070959227A5078908471 @default.
• W2070959227 hasConcept C112418997 @default.
• W2070959227 hasConcept C126322002 @default.
• W2070959227 hasConcept C136764020 @default.
• W2070959227 hasConcept C203014093 @default.
• W2070959227 hasConcept C2775867548 @default.
• W2070959227 hasConcept C2776914184 @default.
• W2070959227 hasConcept C2777014857 @default.
• W2070959227 hasConcept C2777625466 @default.
• W2070959227 hasConcept C2778048844 @default.
• W2070959227 hasConcept C2778371730 @default.
• W2070959227 hasConcept C41008148 @default.
• W2070959227 hasConcept C71924100 @default.
• W2070959227 hasConcept C71928629 @default.
• W2070959227 hasConcept C86803240 @default.
• W2070959227 hasConceptScore W2070959227C112418997 @default.
• W2070959227 hasConceptScore W2070959227C126322002 @default.
• W2070959227 hasConceptScore W2070959227C136764020 @default.
• W2070959227 hasConceptScore W2070959227C203014093 @default.
• W2070959227 hasConceptScore W2070959227C2775867548 @default.
• W2070959227 hasConceptScore W2070959227C2776914184 @default.
• W2070959227 hasConceptScore W2070959227C2777014857 @default.
• W2070959227 hasConceptScore W2070959227C2777625466 @default.
• W2070959227 hasConceptScore W2070959227C2778048844 @default.
• W2070959227 hasConceptScore W2070959227C2778371730 @default.
• W2070959227 hasConceptScore W2070959227C41008148 @default.
• W2070959227 hasConceptScore W2070959227C71924100 @default.
• W2070959227 hasConceptScore W2070959227C71928629 @default.
• W2070959227 hasConceptScore W2070959227C86803240 @default.
• W2070959227 hasIssue "7" @default.
• W2070959227 hasLocation W20709592271 @default.
• W2070959227 hasLocation W20709592272 @default.
• W2070959227 hasOpenAccess W2070959227 @default.
• W2070959227 hasPrimaryLocation W20709592271 @default.
• W2070959227 hasRelatedWork W19576171 @default.
• W2070959227 hasRelatedWork W1990377559 @default.
• W2070959227 hasRelatedWork W2034994870 @default.
• W2070959227 hasRelatedWork W2053593320 @default.
• W2070959227 hasRelatedWork W2084492210 @default.
• W2070959227 hasRelatedWork W2145659413 @default.
• W2070959227 hasRelatedWork W2152004248 @default.

• next