FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070979427> ?p ?o ?g. }

• W2070979427 endingPage "1253" @default.
• W2070979427 startingPage "1247" @default.
• W2070979427 abstract "2,2'-Anhydro-5-ethyluridine (ANEUR), a potent inhibitor of uridine phosphorylase, markedly potentiated the antitumor activity of fluorouridine (FUR) against murine mammary adenocarcinoma 755 in bdf1 mice and human colon adenocarcinoma LS174T in athymic-nude mice. Whereas ANEUR annihilated the antitumor activity of 5-fluoro-2'-deoxyuridine (FUdR) and 5'-deoxy-5-nuorouridine (DFUR) in the murine adenocarcinoma 755 system, it did not alter the antitumor activity of FUdR in the human adenocarcinoma LS174T system. In vitro, ANEUR proved inhibitory to the phosphorolytic cleavage of both FUR and FUdR by uridine phosphorylase, and this could explain why in vivo conversion of FUR and FUdR to 5-fluorouracil was suppressed. FUR can be held directly responsible for the antitumor effects observed in the murine adenocarcinoma 755 system, whereas in the activity against human adenocarcinoma LS174T may be mediated by both FUR and FUdR." @default.
• W2070979427 created "2016-06-24" @default.
• W2070979427 creator A5004390535 @default.
• W2070979427 creator A5029945071 @default.
• W2070979427 creator A5034209147 @default.
• W2070979427 creator A5040662398 @default.
• W2070979427 creator A5045566337 @default.
• W2070979427 creator A5063281154 @default.
• W2070979427 creator A5089007519 @default.
• W2070979427 date "1990-04-01" @default.
• W2070979427 modified "2023-09-22" @default.
• W2070979427 title "Differential effects of 2,2'-anhydro-5-ethyluridine, a uridine phosphorylase inhibitor, on the antitumor activity of 5-fluorouridine and 5-fluoro-2'-deoxyuridine" @default.
• W2070979427 cites W1040045851 @default.
• W2070979427 cites W1455147708 @default.
• W2070979427 cites W1474345297 @default.
• W2070979427 cites W1538923111 @default.
• W2070979427 cites W1571748472 @default.
• W2070979427 cites W1775749144 @default.
• W2070979427 cites W1967137815 @default.
• W2070979427 cites W1975727428 @default.
• W2070979427 cites W1979767153 @default.
• W2070979427 cites W1986924069 @default.
• W2070979427 cites W1997360594 @default.
• W2070979427 cites W2011948343 @default.
• W2070979427 cites W2036997976 @default.
• W2070979427 cites W2067056005 @default.
• W2070979427 cites W2097906802 @default.
• W2070979427 cites W2331948692 @default.
• W2070979427 doi "https://doi.org/10.1016/0006-2952(90)90270-u" @default.
• W2070979427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2138895" @default.
• W2070979427 hasPublicationYear "1990" @default.
• W2070979427 type Work @default.
• W2070979427 sameAs 2070979427 @default.
• W2070979427 citedByCount "19" @default.
• W2070979427 countsByYear W20709794272012 @default.
• W2070979427 countsByYear W20709794272013 @default.
• W2070979427 countsByYear W20709794272016 @default.
• W2070979427 countsByYear W20709794272018 @default.
• W2070979427 countsByYear W20709794272019 @default.
• W2070979427 countsByYear W20709794272020 @default.
• W2070979427 crossrefType "journal-article" @default.
• W2070979427 hasAuthorship W2070979427A5004390535 @default.
• W2070979427 hasAuthorship W2070979427A5029945071 @default.
• W2070979427 hasAuthorship W2070979427A5034209147 @default.
• W2070979427 hasAuthorship W2070979427A5040662398 @default.
• W2070979427 hasAuthorship W2070979427A5045566337 @default.
• W2070979427 hasAuthorship W2070979427A5063281154 @default.
• W2070979427 hasAuthorship W2070979427A5089007519 @default.
• W2070979427 hasConcept C104317684 @default.
• W2070979427 hasConcept C121608353 @default.
• W2070979427 hasConcept C150903083 @default.
• W2070979427 hasConcept C153911025 @default.
• W2070979427 hasConcept C181199279 @default.
• W2070979427 hasConcept C185592680 @default.
• W2070979427 hasConcept C202751555 @default.
• W2070979427 hasConcept C207001950 @default.
• W2070979427 hasConcept C2776694085 @default.
• W2070979427 hasConcept C2776735402 @default.
• W2070979427 hasConcept C2777111502 @default.
• W2070979427 hasConcept C2779598120 @default.
• W2070979427 hasConcept C2780456651 @default.
• W2070979427 hasConcept C2781182431 @default.
• W2070979427 hasConcept C2781259782 @default.
• W2070979427 hasConcept C54355233 @default.
• W2070979427 hasConcept C552990157 @default.
• W2070979427 hasConcept C55493867 @default.
• W2070979427 hasConcept C67705224 @default.
• W2070979427 hasConcept C86803240 @default.
• W2070979427 hasConcept C98274493 @default.
• W2070979427 hasConceptScore W2070979427C104317684 @default.
• W2070979427 hasConceptScore W2070979427C121608353 @default.
• W2070979427 hasConceptScore W2070979427C150903083 @default.
• W2070979427 hasConceptScore W2070979427C153911025 @default.
• W2070979427 hasConceptScore W2070979427C181199279 @default.
• W2070979427 hasConceptScore W2070979427C185592680 @default.
• W2070979427 hasConceptScore W2070979427C202751555 @default.
• W2070979427 hasConceptScore W2070979427C207001950 @default.
• W2070979427 hasConceptScore W2070979427C2776694085 @default.
• W2070979427 hasConceptScore W2070979427C2776735402 @default.
• W2070979427 hasConceptScore W2070979427C2777111502 @default.
• W2070979427 hasConceptScore W2070979427C2779598120 @default.
• W2070979427 hasConceptScore W2070979427C2780456651 @default.
• W2070979427 hasConceptScore W2070979427C2781182431 @default.
• W2070979427 hasConceptScore W2070979427C2781259782 @default.
• W2070979427 hasConceptScore W2070979427C54355233 @default.
• W2070979427 hasConceptScore W2070979427C552990157 @default.
• W2070979427 hasConceptScore W2070979427C55493867 @default.
• W2070979427 hasConceptScore W2070979427C67705224 @default.
• W2070979427 hasConceptScore W2070979427C86803240 @default.
• W2070979427 hasConceptScore W2070979427C98274493 @default.
• W2070979427 hasIssue "7" @default.
• W2070979427 hasLocation W20709794271 @default.
• W2070979427 hasLocation W20709794272 @default.
• W2070979427 hasOpenAccess W2070979427 @default.
• W2070979427 hasPrimaryLocation W20709794271 @default.
• W2070979427 hasRelatedWork W2014212289 @default.
• W2070979427 hasRelatedWork W2035761729 @default.
• W2070979427 hasRelatedWork W2070979427 @default.

• next