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- W2070987189 abstract "Background and Aims: Recently, laparoscopy-assisted gastrectomy (LAG) has been more widely performed for early gastric cancer (EGC). Preoperative accurate evaluation for primary lesion regarding depth of invasion is important for LAG, but multidetector row computed tomography (MDCT) cannot assess the depth of tumor invasion accurately. This study was performed to evaluate the preoperative diagnostic role of endoscopic ultrasonography (EUS) for EGC. Patients and Methods: We prospectively enrolled patients clinically diagnosed as EGC by upper gastrointestinal endoscopy with pathologic examination and EUS. They were also evaluated by MDCT and underwent LAG or open gastrectomy (OG) depending on depth of tumor invasion suggested by MDCT. The diagnostic accuracies of EUS and MDCT for primary lesion and lymph node metastasis were evaluated by comparing with pathologies of surgical specimens using TNM staging system. Results: A total of 51 patients (30 men, mean 53.9 years) were enrolled between August 2005 and October 2006. Forty-three patients among 48 patients who underwent LAG had EGCs (89.6%) and 2 among 3 patients who underwent OG had advanced gastric cancers (66.7%). Mean number of resected lymph nodes was 31.8. The sensitivity of EUS was 65.4% for mucosal cancer and 61.1% for submucosal invading cancer. The positive predictive value of EUS for T1 lesion was 86.3%. As a whole, the accuracy of EUS for depth of tumor invasion was 54.9%, whereas MDCT could not distinguish mucosal or submucosal invading cancer in any cases. The T staging accuracy of EUS was 86.3%, which was not significantly different from that of MDCT (88.2%, p = 1.000). The sensitivity and positive predictive value of EUS for N0 were 100% and 92.0%, respectively. The N staging accuracies of EUS and MDCT were also comparable (90.2% vs. 82.4%, p = 0.219). Conclusions: EUS is useful for the detailed preoperative evaluation of depth of tumor invasion and for the proper decision on performing laparoscopy-assisted gastrectomy for EGC. Large-scaled study is warranted to elucidate the role of EUS for making decisions on the method of curative treatment for gastric cancer." @default.
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- W2070987189 date "2007-04-01" @default.
- W2070987189 modified "2023-10-14" @default.
- W2070987189 title "Diagnostic Accuracy of Endoscopic Ultrasonography in Preoperative Assessment of Early Gastric Cancer for Laparoscopy-Assisted Gastrectomy" @default.
- W2070987189 doi "https://doi.org/10.1016/j.gie.2007.03.410" @default.
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