FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070988759> ?p ?o ?g. }

• W2070988759 abstract "Plasma measurement of cardiac natriuretic peptides constitutes promising markers of congenital heart disease. However, concentrations change rapidly and dramatically during the first days after delivery even in healthy neonates, which complicates clinical interpretation. It is unknown whether these changes in plasma concentrations are explained by corresponding changes in the cardiac gene expression. We quantified the chamber-specific mRNA levels of ANP (A-type natriuretic peptide) and BNP (B-type natriuretic peptide) and plasma pro-ANP and BNP-32 concentrations in healthy piglets during the first 72 hours of life (from 2 litters, n = 44). Chamber-specific ANP and BNP mRNA levels reflected hemodynamic neonate changes at birth but did not correlate with circulating natriuretic peptide concentrations. However, plasma pro-ANP and creatinine concentrations were closely correlated (P < .0001; r = 0.73). Plasma pro-ANP levels were highest on the day of delivery (5580 pmol/L [4320-6786] decreasing to 2484 pmol/L [1602-2898] after 72 hours, P < .0001). During the 72 hours, gel chromatography suggested that the translational products in circulation and in atrial tissue were immature, ie, unprocessed pro-ANP. In contrast to pro-ANP, BNP-32 plasma concentrations were low at delivery and peaked after 48 hours (12 [10.5-20.6] vs. 88.8 [71.7-101.4] pmol/L, P < .0001). To conclude, ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. However, the cardiac gene expression does not explain plasma concentrations." @default.
• W2070988759 created "2016-06-24" @default.
• W2070988759 creator A5007102920 @default.
• W2070988759 creator A5052571062 @default.
• W2070988759 creator A5064814042 @default.
• W2070988759 creator A5068992447 @default.
• W2070988759 creator A5081407287 @default.
• W2070988759 creator A5082553594 @default.
• W2070988759 creator A5085229618 @default.
• W2070988759 date "2013-03-28" @default.
• W2070988759 modified "2023-09-22" @default.
• W2070988759 title "Cardiac Natriuretic Peptide Gene Expression and Plasma Concentrations During the First 72 Hours of Life in Piglets" @default.
• W2070988759 cites W1589112140 @default.
• W2070988759 cites W177249847 @default.
• W2070988759 cites W1965195927 @default.
• W2070988759 cites W1975193208 @default.
• W2070988759 cites W1975969451 @default.
• W2070988759 cites W1977941866 @default.
• W2070988759 cites W1992243367 @default.
• W2070988759 cites W1993390101 @default.
• W2070988759 cites W1999540092 @default.
• W2070988759 cites W2000556566 @default.
• W2070988759 cites W2008508322 @default.
• W2070988759 cites W2009875939 @default.
• W2070988759 cites W2011549250 @default.
• W2070988759 cites W2020944497 @default.
• W2070988759 cites W2041091160 @default.
• W2070988759 cites W2050934730 @default.
• W2070988759 cites W2053458506 @default.
• W2070988759 cites W2057186061 @default.
• W2070988759 cites W2064439430 @default.
• W2070988759 cites W2074874552 @default.
• W2070988759 cites W2096890599 @default.
• W2070988759 cites W2105569743 @default.
• W2070988759 cites W2130973800 @default.
• W2070988759 cites W2138995626 @default.
• W2070988759 cites W2146230234 @default.
• W2070988759 cites W2158083793 @default.
• W2070988759 cites W2161204310 @default.
• W2070988759 cites W2334327302 @default.
• W2070988759 cites W2911339676 @default.
• W2070988759 doi "https://doi.org/10.1210/en.2012-2186" @default.
• W2070988759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23539511" @default.
• W2070988759 hasPublicationYear "2013" @default.
• W2070988759 type Work @default.
• W2070988759 sameAs 2070988759 @default.
• W2070988759 citedByCount "6" @default.
• W2070988759 countsByYear W20709887592014 @default.
• W2070988759 countsByYear W20709887592015 @default.
• W2070988759 countsByYear W20709887592017 @default.
• W2070988759 countsByYear W20709887592018 @default.
• W2070988759 countsByYear W20709887592019 @default.
• W2070988759 crossrefType "journal-article" @default.
• W2070988759 hasAuthorship W2070988759A5007102920 @default.
• W2070988759 hasAuthorship W2070988759A5052571062 @default.
• W2070988759 hasAuthorship W2070988759A5064814042 @default.
• W2070988759 hasAuthorship W2070988759A5068992447 @default.
• W2070988759 hasAuthorship W2070988759A5081407287 @default.
• W2070988759 hasAuthorship W2070988759A5082553594 @default.
• W2070988759 hasAuthorship W2070988759A5085229618 @default.
• W2070988759 hasBestOaLocation W20709887591 @default.
• W2070988759 hasConcept C126322002 @default.
• W2070988759 hasConcept C134018914 @default.
• W2070988759 hasConcept C185592680 @default.
• W2070988759 hasConcept C2775846464 @default.
• W2070988759 hasConcept C2775915353 @default.
• W2070988759 hasConcept C2778069365 @default.
• W2070988759 hasConcept C2778198053 @default.
• W2070988759 hasConcept C56191518 @default.
• W2070988759 hasConcept C71315377 @default.
• W2070988759 hasConcept C71924100 @default.
• W2070988759 hasConceptScore W2070988759C126322002 @default.
• W2070988759 hasConceptScore W2070988759C134018914 @default.
• W2070988759 hasConceptScore W2070988759C185592680 @default.
• W2070988759 hasConceptScore W2070988759C2775846464 @default.
• W2070988759 hasConceptScore W2070988759C2775915353 @default.
• W2070988759 hasConceptScore W2070988759C2778069365 @default.
• W2070988759 hasConceptScore W2070988759C2778198053 @default.
• W2070988759 hasConceptScore W2070988759C56191518 @default.
• W2070988759 hasConceptScore W2070988759C71315377 @default.
• W2070988759 hasConceptScore W2070988759C71924100 @default.
• W2070988759 hasLocation W20709887591 @default.
• W2070988759 hasLocation W20709887592 @default.
• W2070988759 hasOpenAccess W2070988759 @default.
• W2070988759 hasPrimaryLocation W20709887591 @default.
• W2070988759 hasRelatedWork W1975969451 @default.
• W2070988759 hasRelatedWork W1982914013 @default.
• W2070988759 hasRelatedWork W1987477911 @default.
• W2070988759 hasRelatedWork W1992663992 @default.
• W2070988759 hasRelatedWork W1999712109 @default.
• W2070988759 hasRelatedWork W2017748433 @default.
• W2070988759 hasRelatedWork W2035619629 @default.
• W2070988759 hasRelatedWork W2041091160 @default.
• W2070988759 hasRelatedWork W2061466727 @default.
• W2070988759 hasRelatedWork W2068437118 @default.
• W2070988759 hasRelatedWork W2092946225 @default.
• W2070988759 hasRelatedWork W2101692759 @default.
• W2070988759 hasRelatedWork W2106012825 @default.
• W2070988759 hasRelatedWork W2133265225 @default.
• W2070988759 hasRelatedWork W2277969919 @default.

• next