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• W2071003673 abstract "A library of quinoline‐ β ‐lactam‐based hybrids was synthesized and tested for their antimalarial and antitubercular activities. The present antimalarial data showed the dependence of activity on the nature of linker, N ‐1 substituent of the β ‐lactam ring as well as the length of alkyl chain. Most of the compounds are not as efficient as chloroquine in inhibiting the culture growth of Plasmodium falciparum W 2 strain. Nevertheless, the synthesized hybrids showed better antitubercular activities (up to five times) compared with cephalexin (up to three times) and ethionamide." @default.
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• W2071003673 date "2013-10-28" @default.
• W2071003673 modified "2023-10-04" @default.
• W2071003673 title "4-Aminoquinoline-<i>β</i>-Lactam Conjugates: Synthesis, Antimalarial, and Antitubercular Evaluation" @default.
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• W2071003673 doi "https://doi.org/10.1111/cbdd.12225" @default.
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