FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071017066> ?p ?o ?g. }

• W2071017066 abstract "The olefin ethylene is a ubiquitously found gas. It originates predominantly from plants, combustion processes and industrial sources. In mammals, inhaled ethylene is metabolized by cytochrome P450-dependent monooxygenases, particularly by cytochrome P450 2E1, to ethylene oxide, an epoxide that directly alkylates proteins and DNA. Ethylene oxide was mutagenic in vitro and in vivo in insects and mammals and carcinogenic in rats and mice. A physiological toxicokinetic model is a most useful tool for estimating the ethylene oxide burden in ethylene-exposed rodents and humans. The only published physiological toxicokinetic model for ethylene and metabolically produced ethylene oxide is discussed. Additionally, existing data required for the development of a future model and for testing its predictive accuracy are reviewed and extended by new gas uptake studies with ethylene and ethylene oxide in B6C3F1 mice and with ethylene in F344 rats." @default.
• W2071017066 created "2016-06-24" @default.
• W2071017066 creator A5000551036 @default.
• W2071017066 creator A5008812360 @default.
• W2071017066 creator A5011149630 @default.
• W2071017066 creator A5034842213 @default.
• W2071017066 creator A5049198780 @default.
• W2071017066 creator A5068357698 @default.
• W2071017066 creator A5069771802 @default.
• W2071017066 date "2015-11-01" @default.
• W2071017066 modified "2023-10-16" @default.
• W2071017066 title "Novel and existing data for a future physiological toxicokinetic model of ethylene and its metabolite ethylene oxide in mouse, rat, and human" @default.
• W2071017066 cites W15858186 @default.
• W2071017066 cites W1599974519 @default.
• W2071017066 cites W1643871962 @default.
• W2071017066 cites W1963682115 @default.
• W2071017066 cites W1967455724 @default.
• W2071017066 cites W1970651123 @default.
• W2071017066 cites W1972066701 @default.
• W2071017066 cites W1972118534 @default.
• W2071017066 cites W1976430889 @default.
• W2071017066 cites W1978841174 @default.
• W2071017066 cites W1981132325 @default.
• W2071017066 cites W1984526747 @default.
• W2071017066 cites W1987860843 @default.
• W2071017066 cites W1991826393 @default.
• W2071017066 cites W1993785497 @default.
• W2071017066 cites W1994587447 @default.
• W2071017066 cites W1998462172 @default.
• W2071017066 cites W1999248770 @default.
• W2071017066 cites W2001610879 @default.
• W2071017066 cites W2003967168 @default.
• W2071017066 cites W2004841826 @default.
• W2071017066 cites W2006615329 @default.
• W2071017066 cites W2012551500 @default.
• W2071017066 cites W2014363444 @default.
• W2071017066 cites W2015247332 @default.
• W2071017066 cites W2020649487 @default.
• W2071017066 cites W2022471529 @default.
• W2071017066 cites W2023585397 @default.
• W2071017066 cites W2023927250 @default.
• W2071017066 cites W2025331873 @default.
• W2071017066 cites W2025551677 @default.
• W2071017066 cites W2027187135 @default.
• W2071017066 cites W2027596985 @default.
• W2071017066 cites W2029707072 @default.
• W2071017066 cites W2031863702 @default.
• W2071017066 cites W2032724989 @default.
• W2071017066 cites W2035194997 @default.
• W2071017066 cites W2038496518 @default.
• W2071017066 cites W2039042917 @default.
• W2071017066 cites W2039936758 @default.
• W2071017066 cites W2042254166 @default.
• W2071017066 cites W2044587145 @default.
• W2071017066 cites W2045182627 @default.
• W2071017066 cites W2048740254 @default.
• W2071017066 cites W2050934378 @default.
• W2071017066 cites W2053333023 @default.
• W2071017066 cites W2053777138 @default.
• W2071017066 cites W2054015586 @default.
• W2071017066 cites W2054256867 @default.
• W2071017066 cites W2056253423 @default.
• W2071017066 cites W2060136226 @default.
• W2071017066 cites W2068747346 @default.
• W2071017066 cites W2071506487 @default.
• W2071017066 cites W2074918018 @default.
• W2071017066 cites W2078382033 @default.
• W2071017066 cites W2081877948 @default.
• W2071017066 cites W2085829422 @default.
• W2071017066 cites W2088724807 @default.
• W2071017066 cites W2088730390 @default.
• W2071017066 cites W2096441075 @default.
• W2071017066 cites W2105990671 @default.
• W2071017066 cites W2111294689 @default.
• W2071017066 cites W2130980888 @default.
• W2071017066 cites W2139996385 @default.
• W2071017066 cites W2140022101 @default.
• W2071017066 cites W2145099685 @default.
• W2071017066 cites W2146139538 @default.
• W2071017066 cites W2149584328 @default.
• W2071017066 cites W2154115064 @default.
• W2071017066 cites W2155231169 @default.
• W2071017066 cites W2157471387 @default.
• W2071017066 cites W2170554512 @default.
• W2071017066 cites W2287120485 @default.
• W2071017066 cites W2314667127 @default.
• W2071017066 cites W2323335137 @default.
• W2071017066 cites W2324375972 @default.
• W2071017066 cites W2417683051 @default.
• W2071017066 cites W2735570746 @default.
• W2071017066 cites W2955504961 @default.
• W2071017066 cites W599264250 @default.
• W2071017066 cites W70440519 @default.
• W2071017066 doi "https://doi.org/10.1016/j.cbi.2015.04.002" @default.
• W2071017066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25868680" @default.
• W2071017066 hasPublicationYear "2015" @default.
• W2071017066 type Work @default.
• W2071017066 sameAs 2071017066 @default.
• W2071017066 citedByCount "1" @default.
• W2071017066 countsByYear W20710170662018 @default.

• next