Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071043920> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2071043920 endingPage "129" @default.
- W2071043920 startingPage "125" @default.
- W2071043920 abstract "Understanding the complex interaction between human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) requires study of both HLA and KIR diversity in the same population. The presence of KIR genes 2DL1, 2, 3, 4, 5, KIR3DL1, 3DL2, 3DL3, KIR2DS1, 2DS2, 2DS3, 2DS4, 2DS5, KIR3DS1, KIR3DP1, KIR2DP1 was determined in 54 unrelated Mexican Mestizo donors. The PCR sequence-specific oligonucleotide probe One Lambda kit (Luminex) kindly given by J. Lee was used for typing. The software analyses the combination obtained for each of the five exons. Five controls (UCLA DNA exchange) were run as quality control. The gene frequency (GF) was calculated for the 16 KIR loci; the GF of individual genes was 100% for 2DL4, 3DL1, 3DL2, 3DL3, 3DP1. KIR2DL1 (76.43%), KIR2DL2 (37.64%), KIR2DL3 (76.43%), KIR2DL5 (29.29%), KIR3DS1 (23.02%), KIR2DS1 (21.83%), KIR2DS2 (37.64%), KIR2DS3 (50.93%), KIR2DS4 (86.93%), KIR2DS5 (29.29%), KIR2DP1 (86.39%). We observed similar frequencies with Caucasians and Mediterraneans, with exceptions: KIR3DL1 which was present in 100% Mexicans, ranged from 62% to 75% in Caucasians; 2DS3 (50.9%) vs 14-20% 2DS4 (86.39%) vs 65-79% and 2DS5 (29.29%) vs 11-18% in Caucasians. The finding of 23 phenotypes in 54 individuals accounting for both chromosomes, demonstrates the enormous diversity. We found 14 different combinations of stimulatory KIRs in the phenotypes; every subject had at least one stimulatory KIR; in all of them, 2DS4 existed except for one person who may have some new combination: 2DS2 2DS3. Extended family data will offer accurate and precise haplotypes to provide an insight on the significance of ethnic distribution and KIR repertoire." @default.
- W2071043920 created "2016-06-24" @default.
- W2071043920 creator A5007654657 @default.
- W2071043920 creator A5015265692 @default.
- W2071043920 creator A5042033563 @default.
- W2071043920 creator A5053269550 @default.
- W2071043920 creator A5058489598 @default.
- W2071043920 creator A5078990283 @default.
- W2071043920 date "2007-04-01" @default.
- W2071043920 modified "2023-09-28" @default.
- W2071043920 title "Distribution of the killer cell immunoglobulin-like receptors in Mexican Mestizos" @default.
- W2071043920 cites W1974876624 @default.
- W2071043920 cites W1986822630 @default.
- W2071043920 cites W1989412088 @default.
- W2071043920 cites W1990569845 @default.
- W2071043920 cites W2003912772 @default.
- W2071043920 cites W2006279727 @default.
- W2071043920 cites W2006602967 @default.
- W2071043920 cites W2013956181 @default.
- W2071043920 cites W2023072945 @default.
- W2071043920 cites W2076162312 @default.
- W2071043920 cites W2079722355 @default.
- W2071043920 cites W2090036582 @default.
- W2071043920 cites W2125127249 @default.
- W2071043920 cites W2163751839 @default.
- W2071043920 cites W2170106245 @default.
- W2071043920 doi "https://doi.org/10.1111/j.1399-0039.2006.76212.x" @default.
- W2071043920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17445185" @default.
- W2071043920 hasPublicationYear "2007" @default.
- W2071043920 type Work @default.
- W2071043920 sameAs 2071043920 @default.
- W2071043920 citedByCount "19" @default.
- W2071043920 countsByYear W20710439202013 @default.
- W2071043920 countsByYear W20710439202015 @default.
- W2071043920 countsByYear W20710439202016 @default.
- W2071043920 countsByYear W20710439202018 @default.
- W2071043920 crossrefType "journal-article" @default.
- W2071043920 hasAuthorship W2071043920A5007654657 @default.
- W2071043920 hasAuthorship W2071043920A5015265692 @default.
- W2071043920 hasAuthorship W2071043920A5042033563 @default.
- W2071043920 hasAuthorship W2071043920A5053269550 @default.
- W2071043920 hasAuthorship W2071043920A5058489598 @default.
- W2071043920 hasAuthorship W2071043920A5078990283 @default.
- W2071043920 hasConcept C104317684 @default.
- W2071043920 hasConcept C147483822 @default.
- W2071043920 hasConcept C153911025 @default.
- W2071043920 hasConcept C159654299 @default.
- W2071043920 hasConcept C170493617 @default.
- W2071043920 hasConcept C180754005 @default.
- W2071043920 hasConcept C188280979 @default.
- W2071043920 hasConcept C203014093 @default.
- W2071043920 hasConcept C2781209916 @default.
- W2071043920 hasConcept C2908647359 @default.
- W2071043920 hasConcept C36823959 @default.
- W2071043920 hasConcept C54355233 @default.
- W2071043920 hasConcept C71924100 @default.
- W2071043920 hasConcept C86803240 @default.
- W2071043920 hasConcept C99454951 @default.
- W2071043920 hasConceptScore W2071043920C104317684 @default.
- W2071043920 hasConceptScore W2071043920C147483822 @default.
- W2071043920 hasConceptScore W2071043920C153911025 @default.
- W2071043920 hasConceptScore W2071043920C159654299 @default.
- W2071043920 hasConceptScore W2071043920C170493617 @default.
- W2071043920 hasConceptScore W2071043920C180754005 @default.
- W2071043920 hasConceptScore W2071043920C188280979 @default.
- W2071043920 hasConceptScore W2071043920C203014093 @default.
- W2071043920 hasConceptScore W2071043920C2781209916 @default.
- W2071043920 hasConceptScore W2071043920C2908647359 @default.
- W2071043920 hasConceptScore W2071043920C36823959 @default.
- W2071043920 hasConceptScore W2071043920C54355233 @default.
- W2071043920 hasConceptScore W2071043920C71924100 @default.
- W2071043920 hasConceptScore W2071043920C86803240 @default.
- W2071043920 hasConceptScore W2071043920C99454951 @default.
- W2071043920 hasLocation W20710439201 @default.
- W2071043920 hasLocation W20710439202 @default.
- W2071043920 hasOpenAccess W2071043920 @default.
- W2071043920 hasPrimaryLocation W20710439201 @default.
- W2071043920 hasRelatedWork W1969268771 @default.
- W2071043920 hasRelatedWork W2006911013 @default.
- W2071043920 hasRelatedWork W2033539608 @default.
- W2071043920 hasRelatedWork W2038595461 @default.
- W2071043920 hasRelatedWork W2057325260 @default.
- W2071043920 hasRelatedWork W2131411894 @default.
- W2071043920 hasRelatedWork W2142882497 @default.
- W2071043920 hasRelatedWork W2411054033 @default.
- W2071043920 hasRelatedWork W2427947769 @default.
- W2071043920 hasRelatedWork W3127076636 @default.
- W2071043920 hasVolume "69" @default.
- W2071043920 isParatext "false" @default.
- W2071043920 isRetracted "false" @default.
- W2071043920 magId "2071043920" @default.
- W2071043920 workType "article" @default.