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• W2071094711 abstract "The reaction of trans-diamminedichloroplatinum(II), an inactive isomer of cisplatin, with d(TACGTA) was performed in aqueous solution, and the interstrand cross-linked adduct was isolated on a preparative scale. This adduct was characterized by 1 M thiourea treatment, atomic absorption spectroscopy, enzymatic digestion and 1H NMR as platinum coordinated to two molecules of d(TACGTA) at the N7 atom of the guanine residue. This interstrand cross-linked adduct did not form a duplex structure in the conditions where the free hexanucleotide adopts it." @default.
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• W2071094711 date "1991-03-01" @default.
• W2071094711 modified "2023-10-14" @default.
• W2071094711 title "Interstrand cross-linking of the hexadeoxynucleotide d(TACGTA) upon reaction with trans-diamminedichloroplatinum(II)" @default.
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• W2071094711 doi "https://doi.org/10.1016/0006-291x(91)91598-7" @default.
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