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• W2071116105 abstract "Susceptibility of chemical sensors to false positive signals remains a common drawback due to insufficient sensor coating selectivity. By mimicking biology, we have demonstrated the use of sequence-specific biopolymers to generate highly selective receptors for trinitrotoluene and 2,4-dinitrotoluene. Using mutational analysis, we show that the identified binding peptides recognize the target substrate through multivalent binding with key side chain amino acid elements. Additionally, our peptide-based receptors embedded in a hydrogel show selective binding to target molecules in the gas phase. These experiments demonstrate the technique of receptor screening in liquid to be translated to selective gas-phase target binding, potentially impacting the design of a new class of sensor coatings." @default.
• W2071116105 created "2016-06-24" @default.
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• W2071116105 date "2008-03-26" @default.
• W2071116105 modified "2023-10-18" @default.
• W2071116105 title "Evolutionary Screening of Biomimetic Coatings for Selective Detection of Explosives" @default.
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• W2071116105 doi "https://doi.org/10.1021/la7035289" @default.
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