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- W2071200557 abstract "Acute haloperidol administration decreases the number of rat striatal D2 dopamine receptor (D2-receptor). The potential involvement of decreased D2-receptor gene transcription in the above process was examined using Northern blot analysis. There was a dose- and time-dependent transient decrement in the level of striatal D2-receptor mRNA after haloperidol. The decrease in transcription may be mediated via blockade of D2-receptor, since S(−)-sulpiride but not the inactive enantiomer R(+)-sulpiride produced the inhibition." @default.
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- W2071200557 date "1992-07-01" @default.
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- W2071200557 title "Transient decrease in rat striatal D2 dopamine receptor mRNA level after acute haloperidol treatment" @default.
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- W2071200557 doi "https://doi.org/10.1016/0169-328x(92)90185-e" @default.
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