Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071273748> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2071273748 endingPage "135" @default.
- W2071273748 startingPage "128" @default.
- W2071273748 abstract "Using phenyl β-d-galactoside as an acceptor, α-2-l-fucosyltransferase activity was identified in human cervical epithelium with pH optima at 6.0 and 7.2. The different response to p-chloromercuribenzoate, and ability to utilise asialofetuin as an acceptor, suggests the presence of two fucosyltransferases. The acid form is probably involved in glycoprotein synthesis in vivo. At pH 6.0, fucosyltransferase has a temperature optimum of 25°C, requires the presence of Triton X-100 and either manganese or magnesium for maximal activity, and has Km values for GDP-l-[14C]fucose and phenyl β-d-galactoside of 32.1 · 10−6 M and 8.2 · 10−3 M, respectively. Guanosine nucleotides are potent inhibitors of the fucosyltransferase reaction; GDP is a competitive inhibitor while, depending on its concentration, GTP can either inhibit or activate the reaction. The α-l-fucosidase present in cervical tissue has negligible activity towards the enzyme product, phenyl-α-2-l-[14C]fucosyl-β-d-galactoside. The use of high and low molecular weight acceptors indicates the presence of a β-N-acetylglucosaminide α-3-l-fucosyltransferase and an N-acetylgalactosaminide fucosyltransferase." @default.
- W2071273748 created "2016-06-24" @default.
- W2071273748 creator A5027036763 @default.
- W2071273748 creator A5029963879 @default.
- W2071273748 date "1981-07-01" @default.
- W2071273748 modified "2023-09-26" @default.
- W2071273748 title "Glycosyltransferases of the human cervical epithelium I. Characterization of a β-galactoside α-2-l-fucosyltransferase and the identification of a β-N-acetylglucosaminide α-3-l-fucosyltransferase" @default.
- W2071273748 cites W1501822391 @default.
- W2071273748 cites W1510285220 @default.
- W2071273748 cites W1524769057 @default.
- W2071273748 cites W1538441456 @default.
- W2071273748 cites W1542775374 @default.
- W2071273748 cites W1576319170 @default.
- W2071273748 cites W1580023435 @default.
- W2071273748 cites W1594961135 @default.
- W2071273748 cites W1603897676 @default.
- W2071273748 cites W1622976114 @default.
- W2071273748 cites W1775749144 @default.
- W2071273748 cites W1885778179 @default.
- W2071273748 cites W188605103 @default.
- W2071273748 cites W1964310571 @default.
- W2071273748 cites W1964568732 @default.
- W2071273748 cites W1974610253 @default.
- W2071273748 cites W1989105424 @default.
- W2071273748 cites W1989322633 @default.
- W2071273748 cites W1989614280 @default.
- W2071273748 cites W1991487463 @default.
- W2071273748 cites W1992849751 @default.
- W2071273748 cites W1993166839 @default.
- W2071273748 cites W1997825004 @default.
- W2071273748 cites W1999099504 @default.
- W2071273748 cites W2008244788 @default.
- W2071273748 cites W2040841871 @default.
- W2071273748 cites W2079188168 @default.
- W2071273748 cites W2115417373 @default.
- W2071273748 cites W2128986253 @default.
- W2071273748 cites W2155702013 @default.
- W2071273748 cites W2181928384 @default.
- W2071273748 cites W2218584782 @default.
- W2071273748 cites W2258962222 @default.
- W2071273748 cites W2303304651 @default.
- W2071273748 cites W2405799676 @default.
- W2071273748 doi "https://doi.org/10.1016/0005-2744(81)90117-0" @default.
- W2071273748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6168291" @default.
- W2071273748 hasPublicationYear "1981" @default.
- W2071273748 type Work @default.
- W2071273748 sameAs 2071273748 @default.
- W2071273748 citedByCount "24" @default.
- W2071273748 countsByYear W20712737482012 @default.
- W2071273748 crossrefType "journal-article" @default.
- W2071273748 hasAuthorship W2071273748A5027036763 @default.
- W2071273748 hasAuthorship W2071273748A5029963879 @default.
- W2071273748 hasConcept C108625454 @default.
- W2071273748 hasConcept C161019410 @default.
- W2071273748 hasConcept C181199279 @default.
- W2071273748 hasConcept C185592680 @default.
- W2071273748 hasConcept C2776392439 @default.
- W2071273748 hasConcept C2776841590 @default.
- W2071273748 hasConcept C2777762822 @default.
- W2071273748 hasConcept C55493867 @default.
- W2071273748 hasConcept C71240020 @default.
- W2071273748 hasConceptScore W2071273748C108625454 @default.
- W2071273748 hasConceptScore W2071273748C161019410 @default.
- W2071273748 hasConceptScore W2071273748C181199279 @default.
- W2071273748 hasConceptScore W2071273748C185592680 @default.
- W2071273748 hasConceptScore W2071273748C2776392439 @default.
- W2071273748 hasConceptScore W2071273748C2776841590 @default.
- W2071273748 hasConceptScore W2071273748C2777762822 @default.
- W2071273748 hasConceptScore W2071273748C55493867 @default.
- W2071273748 hasConceptScore W2071273748C71240020 @default.
- W2071273748 hasIssue "1" @default.
- W2071273748 hasLocation W20712737481 @default.
- W2071273748 hasLocation W20712737482 @default.
- W2071273748 hasOpenAccess W2071273748 @default.
- W2071273748 hasPrimaryLocation W20712737481 @default.
- W2071273748 hasRelatedWork W136489056 @default.
- W2071273748 hasRelatedWork W1710793728 @default.
- W2071273748 hasRelatedWork W1987618428 @default.
- W2071273748 hasRelatedWork W1991887201 @default.
- W2071273748 hasRelatedWork W2008557803 @default.
- W2071273748 hasRelatedWork W2040841871 @default.
- W2071273748 hasRelatedWork W2066764777 @default.
- W2071273748 hasRelatedWork W2071273748 @default.
- W2071273748 hasRelatedWork W2087767309 @default.
- W2071273748 hasRelatedWork W2510686852 @default.
- W2071273748 hasVolume "660" @default.
- W2071273748 isParatext "false" @default.
- W2071273748 isRetracted "false" @default.
- W2071273748 magId "2071273748" @default.
- W2071273748 workType "article" @default.