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- W2071286061 abstract "We report four patients with cystic fibrosis and fulminant Clostridium difficile–associated colitis: two died, and one required hemicolectomy. Three of four patients carried the N1303K mutation. Severe and fatal C. difficile colitis can occur in cystic fibrosis patients, possibly with a genotype-specific predilection (i.e., N1303K/other). Because cystic fibrosis patients may have a wide spectrum of gastrointestinal symptoms, disease caused by C. difficile must be considered when these patients have acute abdominal pain, diarrhea, or severe leukocytosis. (J Pediatr 1998;132:177-9)" @default.
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- W2071286061 date "1998-01-01" @default.
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- W2071286061 title "Severe Clostridium difficile–associated colitis in young patients with cystic fibrosis" @default.
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- W2071286061 doi "https://doi.org/10.1016/s0022-3476(98)70511-6" @default.
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