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- W2071286404 abstract "<b><i>Background/Aims:</i></b> The aim of the present study was to determine the association between arterial calcification and cerebral microbleeds (CMB) relative to their distribution. <b><i>Methods:</i></b> We identified 834 consecutive patients with acute ischemic stroke or transient ischemic attack who underwent CT angiography and susceptibility-weighted imaging. <b><i>Results:</i></b> Internal carotid artery (ICA) calcification and CMB were found in 660 patients (79.1%) and 335 patients (40.2%), respectively. ICA calcification was independently associated with CMB of any location (odds ratio, OR, 2.86, 95% CI 2.01-4.08, p < 0.0001). The association between calcification and deep CMB was stronger (OR 3.51, 95% CI 2.39-5.14, p < 0.0001). However, ICA calcification was not associated with CMB in a strictly lobar area. <b><i>Conclusion:</i></b> ICA calcification is an independent risk factor for deep CMB but not for a strictly lobar CMB. Our findings might contribute to the elucidation of the pathogenesis of cerebral small vessel disease." @default.
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- W2071286404 date "2014-01-01" @default.
- W2071286404 modified "2023-09-25" @default.
- W2071286404 title "Carotid Artery Calcification Is Associated with Deep Cerebral Microbleeds" @default.
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- W2071286404 doi "https://doi.org/10.1159/000358513" @default.
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