Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071303930> ?p ?o ?g. }
- W2071303930 endingPage "25" @default.
- W2071303930 startingPage "17" @default.
- W2071303930 abstract "Background: The aim of this study was to investigate the occurrence of subclinical atherosclerosis, evaluated by carotid artery intima-media thickness (CIMT) in subjects with newly diagnosed type 2 diabetes. Methods: A total of 167 subjects, 50 newly diagnosed type 2 diabetic subjects and 117 non-diabetic subjects were included in the study. Obese and overweight newly diagnosed type 2 diabetic patients were matched for age and BMI with obese and overweight non-diabetic subjects. Only postmenopausal women were selected. The following biomarkers were analyzed: fasting glucose, HbA1c, fasting insulin, fasting proinsulin, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, adiponectin, leptin, hs-CRP, urine albumin/creatinine ratio. 75 g oral glucose tolerance test was performed in all subjects. Ultrasound imaging was used to evaluate IMT of the common carotid artery. Results: CIMT was greater in newly diagnosed type 2 patients compared to non-diabetic subjects. When analyzed by BMI, the difference regarding CIMT between diabetic and non-diabetic subjects was significant only in overweight subjects, in both sexes. In univariate analysis in men with newly diagnosed type 2 diabetes, CIMT was positively correlated with age, SBP, triglycerides, leptin and negatively correlated with HDL-cholesterol and in women CIMT was positively correlated with SBP and leptin. Independent determinants of CIMT in patients with newly diagnosed type 2 diabetes were in men age (β = 0.556, p = 0.0028) and log leptin (β = 0.393, p = 0.049) and in women systolic blood pressure (β = 0.48, p = 0.026). Conclusions: Subclinical atherosclerosis is present in newly diagnosed type 2 diabetic subjects. Body fat accumulation in men and hypertension in postmenopausal women have a primary role in increase carotid intima-media thickness." @default.
- W2071303930 created "2016-06-24" @default.
- W2071303930 creator A5012059192 @default.
- W2071303930 creator A5027089813 @default.
- W2071303930 creator A5081425475 @default.
- W2071303930 date "2011-01-01" @default.
- W2071303930 modified "2023-10-15" @default.
- W2071303930 title "Relationship between plasma adipokines, inflammation, insulin resistance and subclinical atherosclerosis in newly diagnosed type 2 diabetes" @default.
- W2071303930 cites W1968176696 @default.
- W2071303930 cites W1972246493 @default.
- W2071303930 cites W1972392024 @default.
- W2071303930 cites W1976610229 @default.
- W2071303930 cites W1976829766 @default.
- W2071303930 cites W1978955123 @default.
- W2071303930 cites W1991508789 @default.
- W2071303930 cites W1992865321 @default.
- W2071303930 cites W1994154940 @default.
- W2071303930 cites W2015629742 @default.
- W2071303930 cites W2028568978 @default.
- W2071303930 cites W2028843302 @default.
- W2071303930 cites W2040029253 @default.
- W2071303930 cites W2043261169 @default.
- W2071303930 cites W2049235189 @default.
- W2071303930 cites W2050772837 @default.
- W2071303930 cites W2052912538 @default.
- W2071303930 cites W2070692648 @default.
- W2071303930 cites W2071760362 @default.
- W2071303930 cites W2078412974 @default.
- W2071303930 cites W2082343989 @default.
- W2071303930 cites W2083114835 @default.
- W2071303930 cites W2089753905 @default.
- W2071303930 cites W2090883509 @default.
- W2071303930 cites W2092100251 @default.
- W2071303930 cites W2092339818 @default.
- W2071303930 cites W2119956225 @default.
- W2071303930 cites W2121262506 @default.
- W2071303930 cites W2122975632 @default.
- W2071303930 cites W2124409609 @default.
- W2071303930 cites W2127610524 @default.
- W2071303930 cites W2127667572 @default.
- W2071303930 cites W2129373188 @default.
- W2071303930 cites W2133870378 @default.
- W2071303930 cites W2141600407 @default.
- W2071303930 cites W2144814726 @default.
- W2071303930 cites W2152423563 @default.
- W2071303930 cites W2162060216 @default.
- W2071303930 cites W2166287336 @default.
- W2071303930 cites W2171787024 @default.
- W2071303930 doi "https://doi.org/10.4236/jdm.2011.12004" @default.
- W2071303930 hasPublicationYear "2011" @default.
- W2071303930 type Work @default.
- W2071303930 sameAs 2071303930 @default.
- W2071303930 citedByCount "6" @default.
- W2071303930 countsByYear W20713039302015 @default.
- W2071303930 countsByYear W20713039302016 @default.
- W2071303930 countsByYear W20713039302017 @default.
- W2071303930 countsByYear W20713039302020 @default.
- W2071303930 countsByYear W20713039302023 @default.
- W2071303930 crossrefType "journal-article" @default.
- W2071303930 hasAuthorship W2071303930A5012059192 @default.
- W2071303930 hasAuthorship W2071303930A5027089813 @default.
- W2071303930 hasAuthorship W2071303930A5081425475 @default.
- W2071303930 hasBestOaLocation W20713039301 @default.
- W2071303930 hasConcept C126322002 @default.
- W2071303930 hasConcept C134018914 @default.
- W2071303930 hasConcept C194832188 @default.
- W2071303930 hasConcept C2776782570 @default.
- W2071303930 hasConcept C2777180221 @default.
- W2071303930 hasConcept C2777391703 @default.
- W2071303930 hasConcept C2779306644 @default.
- W2071303930 hasConcept C2779339615 @default.
- W2071303930 hasConcept C2780586474 @default.
- W2071303930 hasConcept C2780613262 @default.
- W2071303930 hasConcept C2987047532 @default.
- W2071303930 hasConcept C511355011 @default.
- W2071303930 hasConcept C555293320 @default.
- W2071303930 hasConcept C71924100 @default.
- W2071303930 hasConcept C90924648 @default.
- W2071303930 hasConceptScore W2071303930C126322002 @default.
- W2071303930 hasConceptScore W2071303930C134018914 @default.
- W2071303930 hasConceptScore W2071303930C194832188 @default.
- W2071303930 hasConceptScore W2071303930C2776782570 @default.
- W2071303930 hasConceptScore W2071303930C2777180221 @default.
- W2071303930 hasConceptScore W2071303930C2777391703 @default.
- W2071303930 hasConceptScore W2071303930C2779306644 @default.
- W2071303930 hasConceptScore W2071303930C2779339615 @default.
- W2071303930 hasConceptScore W2071303930C2780586474 @default.
- W2071303930 hasConceptScore W2071303930C2780613262 @default.
- W2071303930 hasConceptScore W2071303930C2987047532 @default.
- W2071303930 hasConceptScore W2071303930C511355011 @default.
- W2071303930 hasConceptScore W2071303930C555293320 @default.
- W2071303930 hasConceptScore W2071303930C71924100 @default.
- W2071303930 hasConceptScore W2071303930C90924648 @default.
- W2071303930 hasIssue "02" @default.
- W2071303930 hasLocation W20713039301 @default.
- W2071303930 hasOpenAccess W2071303930 @default.
- W2071303930 hasPrimaryLocation W20713039301 @default.
- W2071303930 hasRelatedWork W1979957210 @default.